Results 241 to 250 of about 415,924 (312)

High‐Density E. Coli Cultivation Arrays for Combinatorial Drug Testing With Subsequent Lipid Profiling by MALDI‐MS

open access: yesAdvanced Science, EarlyView.
High‐throughput antibiotic cross‐gradient assays on microdroplet arrays. A multichannel printhead together with five pressure regulators forms droplet arrays of up to 20 832 droplets within 25 minutes. Each droplet contains unique concentrations of antibiotics, allowing to moniture a vast spectrum of bacterial repsonses over night. The bacterial growth
M. Breitfeld   +5 more
wiley   +1 more source

Efficient Polarization‐Entangled Photon‐Pair Generation by a Fiber‐In‐Line van der Waals Material

open access: yesAdvanced Science, EarlyView.
Telecom‐wavelength polarization‐entangled photon pairs are generated in a van der Waals‐material‐integrated all‐fiber device via spontaneous parametric down‐conversion. The demonstrated fiberized quantum light source bridges emerging 2D nonlinear materials and practical quantum photonic systems, opening new opportunities for scalable fiber‐based ...
Jungseok Choi   +11 more
wiley   +1 more source

From Folding Mechanics to Robotic Function: A Unified Modeling Framework for Compliant Origami

open access: yesAdvanced Science, EarlyView.
A geometry‐consistent DDG framework captures compliant origami deformation from rigid‐like folding to soft panel bending. By tuning crease and panel stiffness, bistable snap‐through responses transform into smooth monostable deformation, enabling programmable stability and robot‐scale locomotion.
Bohan Zhang   +7 more
wiley   +1 more source

In Situ Profiling of Nanoscale Strains Uncovers Mechano‐Architectural Predictors of Aging and Osteoarthritis Emergence

open access: yesAdvanced Science, EarlyView.
In situ mechanical loading of osteoarthritis‐prone murine knee joints reveals that spatial alterations in subchondral plate microarchitecture precede cartilage loss and promote a shift from coordinated epiphyseal strain dissipation in healthy joints to focal subchondral strain concentration in osteoarthritis‐prone joints.
Aikta Sharma   +10 more
wiley   +1 more source

Deep Learning Prediction of O‐Glycopeptide Tandem Mass Spectra Enhances O‐Glycoproteomics

open access: yesAdvanced Science, EarlyView.
DeepGPO integrates Transformer and graph neural networks with tailored training strategies, including data augmentation, loss re‐weighting, and pre‐training, to achieve high‐quality O‐glycopeptide MS/MS spectra prediction. The predicted MS/MS spectra are used to localize O‐glycosylation sites from HCD MS/MS data, enhancing O‐glycoproteomics analysis ...
Yu Zong, Yuxin Wang, Liang Qiao
wiley   +1 more source

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