Results 41 to 50 of about 429,055 (263)
Modeling excess zeroes in an integrated analysis of vaccine safety
Human Vaccines & Immunotherapeutics, 2018 In prophylactic vaccine studies in healthy populations, many subjects do not experience a single adverse event (AE). Thus, the number of AEs observed in such clinical trials may be difficult to model because of an excess of zeroes relative to the ...
Roger Maansson +6 more
doaj +1 more source
Sciences, Eaux & Territoires, 2018 Avec environ 92 000 obstacles à l'écoulement répertoriés sur le territoire français, le rétablissement de la connectivité des habitats piscicoles figure aujourd'hui parmi les principaux enjeux des politiques publiques de l'environnement. Si les priorités
J.B. TORTEROTOT, A. CAUDRON
doaj +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Sciences, Eaux & Territoires, 2010 Les espèces les plus menacées font l'objet de plans de restauration visant à retrouver une situation antérieure jugée plus satisfaisante. Mais le changement climatique qui s'est opéré dans certaines régions nécessite de se poser la question de l'utilité ...
E. ROCHARD, G. LASSALLE
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GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Lattice permutations and Poisson-Dirichlet distribution of cycle lengths [PDF]
, 2012 We study random spatial permutations on ℤ3 where each jump x↦π(x) is penalized by a factor e−T∥x−π(x)∥2 . The system is known to exhibit a phase transition for low enough T where macroscopic cycles appear.
Daniel Ueltschi +6 more
core +1 more source
Parasite, 2004 L'examen de Citharinus citharus (Geoffroy Saint-Hilaire, 1809 (Teléostéen, Citharinidae), récolté sur le fleuve Chari au Tchad, a révélé la présence de trois espèces nouvelles de Myxosporidies dont nous donnons ici la description complète : Thelohanellus
Fomena A. +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
A spatial mixed Poisson framework for combination of excess-of-loss and proportional reinsurance contracts [PDF]
, 2009 In this paper a purely theoretical reinsurance model is presented, where the reinsurance contract is assumed to be simultaneously of an excess-of-loss and of a proportional type. The stochastic structure of the set of pairs (claim’s arrival time, claim’s
Cerqueti, R +9 more
core +1 more source
Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora
FEBS Open Bio, EarlyView.This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi +6 more
wiley +1 more source