Results 251 to 260 of about 400,590 (330)
We introduce a novel, ion‐targeted strategy to enhance calcium permeation in voltage gated calcium channels. By directly driving the ions’ coherent collective motion via resonant coupling with a 1.65 THz field, we lower the inter‐site energy barrier, inducing a statistically significant enhancement of ion influx.
Zihao Zhang +6 more
wiley +1 more source
Efficient EM Estimation for the Pogit Model via Polya-Gamma Augmentation. [PDF]
Gutiérrez I, Ramírez S, Jofré L.
europepmc +1 more source
Systematically Engineering for Efficient Production of 3‐Methyl‐1‐Butanol in Escherichia coli
An integrated metabolic engineering strategy was established for high‐level 3‐methyl‐1‐butanol biosynthesis in Escherichia coli. Molecular dynamics‐guided semi‐rational engineering of dihydroxyacid dehydratase uncovered and relieved key catalytic bottlenecks, while adaptive laboratory evolution enhanced strain robustness.
Nanfei Geng +6 more
wiley +1 more source
Autonomous Exploration in Unknown Indoor 2D Environments Using Harmonic Fields and Monte Carlo Integration. [PDF]
Kotsinis D, Karras GC, Bechlioulis CP.
europepmc +1 more source
Poisson intensity parameter estimation for stationary Gibbs point processes [PDF]
Nadia Morsli +1 more
openalex
Growth‐Like Swelling of 2D Precursors for Efficient Fabrication of Complex 3D Microstructures
The growth‐like swelling process fills photocured polymers into the elastomeric microstructures, inducing a significant swelling deformation of microstructures that can be maintained in the absence of solvents. The growth‐like swelling process breaks through the dependence of swelling deformation on the solvents, thereby expanding the application of 3D
Xinkai Zhu +13 more
wiley +1 more source
Crofton Risk and Relative Transactional Entropy. [PDF]
Makowski M, Piotrowski EW.
europepmc +1 more source
SpatialESD: Spatial Ensemble Domain Detection in Spatial Transcriptomics
ABSTRACT Spatial transcriptomics (ST) measures gene expression while preserving spatial context within tissues. One of the key tasks in ST analysis is spatial domain detection, which remains challenging due to the complex structure of ST data and the varying performance of individual clustering methods. To address this, we propose SpatialESD, a Spatial
Hongyan Cao +11 more
wiley +1 more source
Incremental self-organization of spatio-temporal spike pattern detection. [PDF]
Dehghani Habibabadi M +2 more
europepmc +1 more source
Cyclic nucleotide‐gated (CNG) and hyperpolarization‐activated cyclic nucleotide‐gated (HCN) channels share substantial sequence and structural similarity but differ markedly in ion conductance and K+ selectivity. Microsecond‐scale atomistic MD simulations qualitatively reproduced the conductance differences observed in single‐channel recordings and ...
Haoran Liu +3 more
wiley +1 more source

