Results 51 to 60 of about 1,930 (169)
We studied the in vitro and in planta antiviral activity of the PhRIP I, a type 1 Ribosome-Inactivating Protein originally purified from leaves of the Phytolacca heterotepala.
ANTIMO DI MARO +6 more
core +1 more source
A crude acetone extract of the pit of date palm (Phoenix dactylifera L.) was prepared and its antiviral activity evaluated against lytic Pseudomonas phage ATCC 14209‐B1, using Pseudomonas aeruginosa ATCC 25668 as the host cell. The antiviral activity of date pits was found to be mediated by binding to the phage, with minimum inhibitory concentration ...
Sabah A. A. Jassim, Mazen A. Naji
wiley +1 more source
Objective. To evaluate the safety of the antimicrobial peptide, lactocin 160. Methods. Lactocin 160, a product of vaginal probiotic Lactobacillus rhamnosus 160 was evaluated for toxicity and irritation. An in vitro human organotypic vaginal‐ectocervical tissue model (EpiVaginal) was employed for the safety testing by determining the exposure time to ...
Sara E. Dover +3 more
wiley +1 more source
Pokeweed antiviral protein (PAP) is a protein known to inactivate eukaryotic ribosomes by an unknown enzymatic action and inhibit the production of mammalian viruses in tissue culture. This protein was subjected to a variety of chemical modifications to determine their effects upon ribosomal inactivation, antiviral action, and cytotoxicity.
Irvin, James D., Aron, Gary M.
openaire +2 more sources
Bioactive peptides (BAPs) obtained from plants and microbes have been thoroughly explored and studied due to their prophylactic properties. The use of BAPs seems to be a promising substitute for several currently available antibiotics because of their antimicrobial properties against foodborne pathogens.
Anowar Khasru Parvez +9 more
wiley +1 more source
Immunology and Homeopathy. 2. Cells of the Immune System and Inflammation
Here we describe the results of some experimental laboratory studies aimed at verifying the efficacy of high dilutions of substances and of homeopathic medicines in models of inflammation and immunity. Studies carried out on basophils, lymphocytes, granulocytes and fibroblasts are reviewed. This approach may help to test under controlled conditions the
Paolo Bellavite +3 more
wiley +1 more source
Broad-spectrum virus resistance in transgenic plants expressing pokeweed antiviral protein. [PDF]
Exogenous application of pokeweed antiviral protein (PAP), a ribosome-inhibiting protein found in the cell walls of Phytolacca americana (pokeweed), protects heterologous plants from viral infection. A cDNA clone for PAP was isolated and introduced into tobacco and potato plants by transformation with Agrobacterium tumefaciens.
Lodge JK, Kaniewski WK, Tumer NE.
europepmc +4 more sources
Expression of a pokeweed antiviral protein in Escherichia coli and its characterization [PDF]
Two expression vectors were constructed to produce a putative mature α‐pokeweed antiviral protein (α‐PAP) in Escherichia coli with its NH2‐ and COOH‐terminal extrapeptides excised. One was for its intracellular expression with a methionine at its NH2‐terminal. The other was for its secretion using an ompA signal peptide. The former product was purified
Kataoka, Jiro +6 more
openaire +2 more sources
Monoclonal Antibodies as Immune Modulators for Cancer Therapy
Monoclonal antibodies may modulate immune and/or biological responses alone, or as carriers of specific agents. Monoclonal antibodies directed against tumours may be indirectly cytotoxic by modulation of antibody‐dependent, cell‐mediated cytotoxicity or complement‐mediated cytotoxicity.
Robert O Dillman
wiley +1 more source
A double safety lock tumor-specific device for suicide gene therapy in breast cancer [PDF]
Producción CientíficaThe complexity and continuous evolution of cancer make the design of novel strategies of treatment a constant challenge in biomedicine.
Arias Vallejo, Francisco Javier +5 more
core +2 more sources

