Results 41 to 50 of about 1,905 (165)
Modeling and Alanine Scanning Mutagenesis Studies of Recombinant Pokeweed Antiviral Protein [PDF]
Journal of Biological Chemistry, 2000 The Phytolacca americana-derived naturally occurring ribosome inhibitory protein pokeweed antiviral protein (PAP) is an N-glycosidase that catalytically removes a specific adenine residue from the stem loop of ribosomal RNA. We have employed molecular modeling studies using a novel model of PAP-RNA complexes and site-directed mutagenesis combined with ...
F, Rajamohan +3 more
openaire +2 more sources
Case Reports in Pathology, Volume 2017, Issue 1, 2017., 2017 Non‐Hodgkin’s lymphoma (NHL) is a common malignancy of childhood; however, a lung primary presentation is an uncommon finding, as is finding an association with the Epstein‐Barr virus (EBV). We report the case of a 23‐month‐old female who developed EBV‐associated diffuse large B‐cell lymphoma (DLBCL) that was initially thought to be pneumonia ...
Eric X. Wei +4 more
wiley +1 more source
Cytokine and immunoglobulin production by PWM-stimulated peripheral and tumor-infiltrating lymphocytes of undifferentiated nasopharyngeal carcinoma (NPC) patients [PDF]
, 2004 Background Undifferentiated Nasopharyngeal Carcinoma (NPC) patients show a characteristic pattern of antibody responses to the Epstein-Barr virus (EBV) which is regularly associated with this tumor.
Lilia Fliss-Jaber +41 more
core +2 more sources
Immunomodulation and Anti‐Inflammatory Effects of Garlic Compounds
Journal of Immunology Research, Volume 2015, Issue 1, 2015., 2015 The benefits of garlic to health have been proclaimed for centuries; however, only recently have Allium sativum and its derivatives been proposed as promising candidates for maintaining the homeostasis of the immune system. The complex biochemistry of garlic makes it possible for variations in processing to yield different preparations with differences
Rodrigo Arreola +7 more
wiley +1 more source
Journal of Viruses, Volume 2014, Issue 1, 2014., 2014 This paper highlights various reasons of evolution of new mutants/variants of JE virus and its effects on neurovirulence, antigenicity, host immune responses, and disease transmission in endemic areas. Virus is reorganizing its genome by making sequence alterations, single site mutations, cluster specific reversions, and amino acid substitutions in ...
Ravi Kant Upadhyay, Piet Maes
wiley +1 more source
Inhibition of herpes simplex virus DNA synthesis by pokeweed antiviral protein [PDF]
Antimicrobial Agents and Chemotherapy, 1983 Pokeweed antiviral protein at a concentration of 3 microM inhibited both the synthesis and release of infectious herpes simplex virus type 1 in cell culture by 90 and 99%, respectively. Addition of pokeweed antiviral protein to Vero cell monolayers before virus infection was 10 to 15% more effective in reducing virus yields than was the simultaneous ...
G J, Teltow, J D, Irvin, G M, Aron
openaire +2 more sources
, 2008 We studied the in vitro and in planta antiviral activity of the PhRIP I, a type 1 Ribosome-Inactivating Protein originally purified from leaves of the Phytolacca heterotepala.
ANTIMO DI MARO +6 more
core +1 more source
An Update in the Use of Antibodies to Treat Glioblastoma Multiforme
Autoimmune Diseases, Volume 2013, Issue 1, 2013., 2013 Glioblastoma is a deadly brain disease and modest improvement in survival has been made. At initial diagnosis, treatment consists of maximum safe surgical resection, followed by temozolomide and chemoirradiation or adjuvant temozolomide alone. However, these treatments do not improve the prognosis and survival of patients.
Norma Y. Hernández-Pedro +5 more
wiley +1 more source
Plant Ribosomal Proteins, RPL12 and RPL19, Play a Role in Nonhost Disease Resistance against Bacterial Pathogens [PDF]
, 2016 Characterizing the molecular mechanism involved in nonhost disease resistance is important to understand the adaptations of plant-pathogen interactions.
Keri Wang +4 more
core +2 more sources
Clinical &Translational Immunology, Volume 15, Issue 5, 2026.We report on a patient homozygous for a novel autosomal recessive loss‐of‐function CARD11 variant, with susceptibility to live attenuated virus (LAV) vaccines and impaired clearance of multiple naturally acquired respiratory viral infections. Inborn errors of immunity affecting the CARD11‐BCL10‐MALT1 (CBM) complex should be considered in individuals ...
Hamish Anderson +12 more
wiley +1 more source