Results 41 to 50 of about 3,449,279 (150)

Evolution of New Variants/Mutants of JE Virus, Its Effect on Neurovirulence, Antigenicity, Host Immune Responses and Disease Transmission in Endemic Areas

Journal of Viruses, Volume 2014, Issue 1, 2014., 2014
This paper highlights various reasons of evolution of new mutants/variants of JE virus and its effects on neurovirulence, antigenicity, host immune responses, and disease transmission in endemic areas. Virus is reorganizing its genome by making sequence alterations, single site mutations, cluster specific reversions, and amino acid substitutions in ...
Ravi Kant Upadhyay, Piet Maes
wiley   +1 more source

Inhibition of herpes simplex virus DNA synthesis by pokeweed antiviral protein [PDF]

Antimicrobial Agents and Chemotherapy, 1983
Pokeweed antiviral protein at a concentration of 3 microM inhibited both the synthesis and release of infectious herpes simplex virus type 1 in cell culture by 90 and 99%, respectively. Addition of pokeweed antiviral protein to Vero cell monolayers before virus infection was 10 to 15% more effective in reducing virus yields than was the simultaneous ...
G J, Teltow, J D, Irvin, G M, Aron
openaire   +2 more sources

An Update in the Use of Antibodies to Treat Glioblastoma Multiforme

Autoimmune Diseases, Volume 2013, Issue 1, 2013., 2013
Glioblastoma is a deadly brain disease and modest improvement in survival has been made. At initial diagnosis, treatment consists of maximum safe surgical resection, followed by temozolomide and chemoirradiation or adjuvant temozolomide alone. However, these treatments do not improve the prognosis and survival of patients.
Norma Y. Hernández-Pedro, Edgar Rangel-López, Gustavo Vargas Félix, Benjamín Pineda, Julio Sotelo, Cristoforo Comi   +5 more
wiley   +1 more source

In Vitro Evaluation of the Antiviral Activity of an Extract of Date Palm (Phoenix dactylifera L.) Pits on a Pseudomonas Phage

Evidence-Based Complementary and Alternative Medicine, Volume 7, Issue 1, Page 57-62, 2010., 2010
A crude acetone extract of the pit of date palm (Phoenix dactylifera L.) was prepared and its antiviral activity evaluated against lytic Pseudomonas phage ATCC 14209‐B1, using Pseudomonas aeruginosa ATCC 25668 as the host cell. The antiviral activity of date pits was found to be mediated by binding to the phage, with minimum inhibitory concentration ...
Sabah A. A. Jassim, Mazen A. Naji
wiley   +1 more source

Modeling and Alanine Scanning Mutagenesis Studies of Recombinant Pokeweed Antiviral Protein [PDF]

Journal of Biological Chemistry, 2000
The Phytolacca americana-derived naturally occurring ribosome inhibitory protein pokeweed antiviral protein (PAP) is an N-glycosidase that catalytically removes a specific adenine residue from the stem loop of ribosomal RNA. We have employed molecular modeling studies using a novel model of PAP-RNA complexes and site-directed mutagenesis combined with ...
F, Rajamohan, M J, Pugmire, I V, Kurinov, F M, Uckun   +3 more
openaire   +2 more sources

Phytohormones and emerging plant growth regulators in tailoring plant immunity against viral infections

Physiologia Plantarum, Volume 177, Issue 2, March/April 2025.
Abstract Viral infections are major contributors to crop yield loss and represent a significant threat to sustainable agriculture. Plants respond to virus attacks by activating sophisticated signalling cascades that initiate multiple defence mechanisms.
Kritika Shukla, Nikita, Altaf Ahmad, Md Salik Noorani, Ravi Gupta   +4 more
wiley   +1 more source

Safety Study of an Antimicrobial Peptide Lactocin 160, Produced by the Vaginal Lactobacillus rhamnosus

Infectious Diseases in Obstetrics and Gynecology, Volume 2007, Issue 1, 2007., 2007
Objective. To evaluate the safety of the antimicrobial peptide, lactocin 160. Methods. Lactocin 160, a product of vaginal probiotic Lactobacillus rhamnosus 160 was evaluated for toxicity and irritation. An in vitro human organotypic vaginal‐ectocervical tissue model (EpiVaginal) was employed for the safety testing by determining the exposure time to ...
Sara E. Dover, Alla A. Aroutcheva, S. Faro, Michael L. Chikindas   +3 more
wiley   +1 more source

Synergistic anti-Newcastle disease virus activity of pokeweed antiviral protein, ribavirin, and guanidine

, 1998
Pokeweed antiviral protein (PAP), in combination with either guanidine or ribavirin, exhibited both synergy and antagonism toward the replication of Newcastle disease virus.
Eric Weaver, Gary M Aron
core   +1 more source

Microbial‐ and Plant‐Derived Bioactive Peptides and Their Applications against Foodborne Pathogens: Current Status and Future Prospects

International Journal of Microbiology, Volume 2024, Issue 1, 2024.
Bioactive peptides (BAPs) obtained from plants and microbes have been thoroughly explored and studied due to their prophylactic properties. The use of BAPs seems to be a promising substitute for several currently available antibiotics because of their antimicrobial properties against foodborne pathogens.
Anowar Khasru Parvez, Fatema Tuz Jubyda, Mohammed Ayaz, Amily Sarker, Nabila Haque, Md. Shahriar Khan, Taslin Jahan Mou, Md. Atikur Rahman, Md. Amdadul Huq, Giuseppe Comi   +9 more
wiley   +1 more source

Immunology and Homeopathy. 2. Cells of the Immune System and Inflammation

Evidence-Based Complementary and Alternative Medicine, Volume 3, Issue 1, Page 13-24, 2006., 2006
Here we describe the results of some experimental laboratory studies aimed at verifying the efficacy of high dilutions of substances and of homeopathic medicines in models of inflammation and immunity. Studies carried out on basophils, lymphocytes, granulocytes and fibroblasts are reviewed. This approach may help to test under controlled conditions the
Paolo Bellavite, Anita Conforti, Francesco Pontarollo, Riccardo Ortolani   +3 more
wiley   +1 more source