Results 21 to 30 of about 3,449,279 (150)
Antiviral foods in the battle against viral infections: Understanding the molecular mechanism
Food Science &Nutrition, Volume 11, Issue 8, Page 4444-4459, August 2023., 2023 Regular intake of antiviral foods may prevent future pandemic and the use of antiviral food with traditional medicine may reduce the severity of viral diseases. Abstract Viruses produce a variety of illnesses, which may also cause acute respiratory syndrome. All viral infections, including COVID‐19, are associated with the strength of the immune system.
Md. Shofiul Azam +4 more
wiley +1 more source
T‐cell recovery and evidence of persistent immune activation 12 months after severe COVID‐19
Allergy, Volume 77, Issue 8, Page 2468-2481, August 2022., 2022 In a multicentric cohort of 173 COVID‐19 patients followed‐up to 1 year we found evidence of functional and numeric T cell recovery. COVID‐19 patients showed persistent moderate T cell activation at follow‐up timepoints. A subgroup of severe COVID‐19 patients exhibited low CD8+ T cell counts at follow‐up, coupled to an inflammatory immune signature and
Patrick Taeschler +14 more
wiley +1 more source
Profound dysregulation of T cell homeostasis and function in patients with severe COVID‐19
Allergy, Volume 76, Issue 9, Page 2866-2881, September 2021., 2021 In severe COVID‐19 T cell populations show perturbations, including loss of naïve T cells, CD4+ T cell skewing toward T follicular helper and cytotoxic phenotypes and expansion of activated and exhausted T cells. Apoptosis and migration contribute to the lymphopenia of severe disease, which is accompanied by Interleukin‐7 elevation.
Sarah Adamo +15 more
wiley +1 more source
Natural Products with Inhibitory Activity against Human Immunodeficiency Virus Type 1
Advances in Virology, Volume 2021, Issue 1, 2021., 2021 Infections caused by human immunodeficiency virus (HIV) are considered one of the main public health problems worldwide. Antiretroviral therapy (ART) is the current modality of treatment for HIV‐1 infection. It comprises the combined use of several drugs and can decrease the viral load and increase the CD4+ T cell count in patients with HIV‐1 infection,
Maria S. Serna-Arbeláez +6 more
wiley +1 more source
Evidence-Based Complementary and Alternative Medicine, Volume 2021, Issue 1, 2021., 2021 This review provides an updated and comprehensive overview on the ethnomedicinal use, phytochemistry, pharmacology, and toxicology of M. loriformis. Phytochemical analysis of M. loriformis revealed that it is composed of phenolics, flavonoids, condensed tannins, chlorophylls, alkaloids, and steroids.
Intan Soraya Che Sulaiman +3 more
wiley +1 more source
Actions of Pokeweed Antiviral Protein on Virus-infected Protoplasts [PDF]
Bioscience, Biotechnology, and Biochemistry, 1997 Pokeweed antiviral protein (PAP) belongs to a group of ribosome-inactivating proteins (RIPs) that inactivate ribosomes by depurinating rRNA at a specific site. To study the mechanism for the antiviral activity of PAP, the actions of PAP on TMV-infected and uninfected tobacco protoplasts were investigated.
WATANABE, Keiichi +3 more
openaire +2 more sources
BMC Biotechnology, 2018 Background Ricin A chain (RTA) and Pokeweed antiviral proteins (PAPs) are plant-derived N-glycosidase ribosomal-inactivating proteins (RIPs) isolated from Ricinus communis and Phytolacca Americana respectively. This study was to investigate the potential
Yasser Hassan, Sherry Ogg, Hui Ge
doaj +1 more source
Pokeweed Antiviral Protein Accesses Ribosomes by Binding to L3 [PDF]
Journal of Biological Chemistry, 1999 Pokeweed antiviral protein (PAP), a 29-kDa ribosome-inactivating protein, catalytically removes an adenine residue from the conserved alpha-sarcin loop of the large rRNA, thereby preventing the binding of eEF-2.GTP complex during protein elongation. Because the alpha-sarcin loop has been placed near the peptidyltransferase center in Escherichia coli ...
K A, Hudak, J D, Dinman, N E, Tumer
openaire +2 more sources
Molecular Plant Pathology, Volume 21, Issue 9, Page 1212-1226, September 2020., 2020 Application or overexpression of α‐MMC in Nicotiana benthamiana increased resistance to TMV infection by means of modulating ROS homeostasis through controlling the expression of antioxidant enzyme‐encoding genes. Abstract Alpha‐momorcharin (α‐MMC), a member of the plant ribosomal inactivating proteins (RIPs) family, has been proven to exhibit ...
Feng Zhu +5 more
wiley +1 more source
The pokeweed leaf mRNA transcriptome and its regulation by jasmonic acid.
Frontiers in Plant Science, 2016 The American pokeweed plant, Phytolacca americana, is recognized for synthesizing pokeweed antiviral protein (PAP), a ribosome inactivating protein (RIP) that inhibits the replication of several plant and animal viruses.
Kira C.M. Neller +2 more
doaj +1 more source