Results 51 to 60 of about 1,905 (165)
A crude acetone extract of the pit of date palm (Phoenix dactylifera L.) was prepared and its antiviral activity evaluated against lytic Pseudomonas phage ATCC 14209‐B1, using Pseudomonas aeruginosa ATCC 25668 as the host cell. The antiviral activity of date pits was found to be mediated by binding to the phage, with minimum inhibitory concentration ...
Sabah A. A. Jassim, Mazen A. Naji
wiley +1 more source
Objective. To evaluate the safety of the antimicrobial peptide, lactocin 160. Methods. Lactocin 160, a product of vaginal probiotic Lactobacillus rhamnosus 160 was evaluated for toxicity and irritation. An in vitro human organotypic vaginal‐ectocervical tissue model (EpiVaginal) was employed for the safety testing by determining the exposure time to ...
Sara E. Dover +3 more
wiley +1 more source
Pokeweed Antiviral Protein Inhibits Brome Mosaic Virus Replication in Plant Cells [PDF]
Pokeweed antiviral protein (PAP) is a ribosome-inactivating protein isolated from the pokeweed plant (Phytolacca americana) that inhibits the proliferation of several plant and animal viruses. We have shown previously that PAP and nontoxic mutants of PAP can directly depurinate brome mosaic virus (BMV) RNA in vitro, resulting in reduced viral protein ...
Daniel, Picard +2 more
openaire +2 more sources
Bioactive peptides (BAPs) obtained from plants and microbes have been thoroughly explored and studied due to their prophylactic properties. The use of BAPs seems to be a promising substitute for several currently available antibiotics because of their antimicrobial properties against foodborne pathogens.
Anowar Khasru Parvez +9 more
wiley +1 more source
Immunology and Homeopathy. 2. Cells of the Immune System and Inflammation
Here we describe the results of some experimental laboratory studies aimed at verifying the efficacy of high dilutions of substances and of homeopathic medicines in models of inflammation and immunity. Studies carried out on basophils, lymphocytes, granulocytes and fibroblasts are reviewed. This approach may help to test under controlled conditions the
Paolo Bellavite +3 more
wiley +1 more source
Monoclonal Antibodies as Immune Modulators for Cancer Therapy
Monoclonal antibodies may modulate immune and/or biological responses alone, or as carriers of specific agents. Monoclonal antibodies directed against tumours may be indirectly cytotoxic by modulation of antibody‐dependent, cell‐mediated cytotoxicity or complement‐mediated cytotoxicity.
Robert O Dillman
wiley +1 more source
Testing of disease-resistance of pokeweed antiviral protein gene (PacPAP) in transgenic cucumber (Cucumis sativus) [PDF]
Transformation of pokeweed antiviral protein gene (PAP) into plants was shown to improve plant resistance to several viruses or fungi pathogens with no much negative effect on plant growth.
Cao, B +6 more
core +2 more sources
Comparative in vitro imunotoxicology of acyclovir and other antiviral agents [PDF]
In vitro lymphocyte blastogenic responses to the commonly employed mitogens phytohemagglutinin, pokeweed, and concanavalin A were evaluated when acyclovir, adenine arabinoside, cytosine arabinoside, and idoxuridine were added to the culture materials ...
Steele, Russell W. +2 more
core
Pharmaceutical Crops: An Overview [PDF]
Pharmaceutical crops is an ambiguous term used by biologists and chemists for different categories of plants. We define pharmaceutical crops as those cultivated species that are used for extraction or preparation of therapeutic substances such as active ...
Antoun, Mikhail +5 more
core +1 more source
Expression and activity of a recombinant chimeric protein composed of pokeweed antiviral protein and of human interleukin‐2 [PDF]
The pokeweed antiviral protein (PAP) has already been used to chemically construct immunotoxins. Here we tested the recombinant approach for the production of PAP‐containing cytotoxic fusion‐proteins. A cDNA encoding a mutated PAP (PAP9), which is expressed at high levels in bacteria, was fused to human interleukin‐2 (IL‐2) cDNA.
Dore, Jean-Michel +2 more
openaire +2 more sources

