The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Preliminary Study on Treatment of Contaminated Groundwater from the Taylorville Gasifier Site [PDF]
Groundwater and soil at the site of an abandoned coal gasification plant in Taylorville, Illinois have been contaminated with compounds associated with coal conversion process waters.
Meuller, Paul A. +2 more
core
Searching speeds and the energetic feasibility of an obligate whale-scavenging fish [PDF]
Two recently published models reach opposite conclusions on the energetic feasibility of a scavenging fish that specialises oil whale carcasses. We argue that the key difference between these models lies in their estimate of the likely searching speed of
Bagley +21 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
2018 State-of the Science of Dispersants and Dispersed Oil (DDO) in U.S. Arctic Waters: Eco-Toxicity and Sublethal Impacts [PDF]
Chemical dispersants were employed on an unprecedented scale during the Deepwater Horizon oil spill in the Gulf of Mexico, and could be a response option should a large spill occur in Arctic waters. The use of dispersants in response to that spill raised
Coastal Response Research Center (CRRC)
core +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Protein genes in repetitive sequence—antifreeze glycoproteins in Atlantic cod genome
Background Highly repetitive sequences are the bane of genome sequence assembly, and the short read lengths produced by current next generation sequencing technologies further exacerbates this obstacle.
Zhuang Xuan +3 more
doaj +1 more source
Study of SENT specimens with a tilted notch to evaluate ductile tearing in spiral welded pipeline applications [PDF]
There is an increasing interest for the use of spiral welded pipelines in strain based design applications. Environmentally imposed loads are able to plastically deform the pipelines, meaning that their structural response is of the utmost importance ...
De Waele, Wim +4 more
core +2 more sources
Antioxidant defenses in polar cod (Boreogadus saida) and responsiveness toward dietary crude oil exposure [PDF]
Increasing anthropogenic activities in the Arctic pose the risk for accidental oil spills but our knowledge of ecotoxicological effects is still limited for Arctic organisms. This study aimed to provide insights in baseline levels of antioxidants in polar cod (Boreogadus saida) from different Arctic locations and investigate the susceptibility of this ...
Ireen Vieweg +4 more
openaire +3 more sources

