Results 131 to 140 of about 201,320 (259)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Analysis of strong polar compounds in extract of Gardenia jasminoisdes fruit using hydrophilic interaction liquid chromatography with evaporative light-scattering detection

open access: yes, 2007
The hydrophilic interaction liquid chromatography (HILIC) is an alternative HPLC mode for separation of polar compounds with polar stationary phases like NP-HPLC but aqueous mobile phase similar to RP-HPLC mode.
章飞芳   +4 more
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Influence of vascular plant photosynthetic rate on CH4 emission from peat monoliths from southern boreal Sweden

open access: yes, 1999
Peat monoliths taken from a boreal peatland system were incubated at two different light intensities to investigate the effect of the photosynthetic rate of vascular plants (Eriophorum angustifolium) on net CH4 emission. The experimental set-up consisted
Joabsson, Anna   +3 more
core   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

On the formation and processing of carbon and nitrogen compounds in carbonaceous chondrites

open access: yes, 1990
On the basis of chemical kinetic consideration, we examine processing of carbon and nitrogen compounds that leads to the linear relation between the logarithmic contents of C and N in carbonaceous chondrites: log N=a log C-b, found by A. Shimoyama et al.
Yamamoto, Tetsuo   +3 more
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Susceptibility of virulent and resistant Escherichia coli strains to non-polar and polar compounds identified in Microplumeria anomala. [PDF]

open access: yesVet World, 2020
Camargo LRP   +8 more
europepmc   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

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