Results 131 to 140 of about 130,570 (300)

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Polar Coordinates: A Standard Area Problem [PDF]

, 2016
Educação Superior::Ciências Exatas e da Terra::MatemáticaThe resource shows a ray, moving along the curve r = 2 sin 3θ, describing the area of the region outlined by it, but outside the region outlined by the curve r = 1Knowledge of polar coordenates are
Talman, Louis A.
core   +2 more sources

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

"Preparation of trans-1,4-polybutadiene-block-polymethyl methacrylate based on coordinative chain transfer polymerization"

Hecheng xiangjiao gongye
"High trans-1,4-selective coordination chain transfer polymerization of butadiene was achieved through the catalysis of isopropoxyl neodymium/n-butyl magnesium catalyst system, the non-polar-polar diblock copolymer of trans-1,4-polybutadiene and ...
ZHENG Wen-jie1, TAN Zhong-yang1, ZHANG Xue-quan2
doaj   +1 more source

Discovery of Spin-pulse Correlated Magnetic Gating Bursts in the Long-period Intermediate Polar PBC J0801.2–4625

The Astrophysical Journal
We present the first discovery of small-amplitude (tens of millimagnitudes), short-duration (several hours) episodic brightenings in the Transiting Exoplanet Survey Satellite (TESS) light curve of the intermediate polar PBC J0801.2–4625 that are strongly
Vishal Joshi, Akash Sundriyal
doaj   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

基于啮合角函数的非圆齿轮重合度求解

Jixie chuandong, 2009
An analysis of the contact ratio of non-circular gear is described.Firstly,the analytical models of tooth profiles and addendum curve are developed geometrically.Then the relationship between contact ratio and polar angle is established.Furthermore the ...
王雷, 张瑞, 苏智剑
doaj  

The Polar Vortex Hypothesis: Evolving, Spectrally Distinct Polar Regions Explain Short- and Long-term Light-curve Evolution and Color–Inclination Trends in Brown Dwarfs and Giant Exoplanets

The Astrophysical Journal Letters
Recent studies revealed viewing-angle-dependent color and spectral trends in brown dwarfs, as well as long-term photometric variability (∼100 hr). The origins of these trends are yet unexplained.
Nguyen Fuda, Dániel Apai
doaj   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source