Results 61 to 70 of about 130,570 (300)

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

The external magnetic sources over the polar caps - Feasible modelling unrealistic expectations

open access: yesAnnals of Geophysics, 1999
No average status can be defined for the sources of the external magnetic field over the polar caps, no index can provide with any such model, the observation of no single quantity or parameter can give the ultimate solution.
G. P. Gregori
doaj   +1 more source

Polar dust obscuration in broad-line active galaxies from the XMM-XXL field [PDF]

open access: yes, 2021
12 pages, 11 figures, accepted for publication in Astronomy & AstrophysicsInternational audienceDust is observed in the polar regions of nearby AGN and it is known to contribute substantially to their mid-IR emission and to the obscuration of their UV to
Theulé, Patrice   +25 more
core   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

Photosynthetic characteristics of phytoplankton off Adelie Land, Antarctica, during the austral summer [PDF]

open access: yes, 2000
P(論文)The photosynthesis-irradiance characteristics (P-E curves) and quantum yields of natural phytoplankton were investigated in the Southern Ocean off Adelie Land, Antarctica, during the austral summer.
Hirawake, Toru   +3 more
core   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

On the singularities of polar curves [PDF]

open access: yesManuscripta Mathematica, 1983
Preprint enviat per a la seva publicació en una revista científica; Manuscripta mathematica, 1983, volume 43, pp. 167–190. [https://doi.org/10.1007/BF01165829]
openaire   +3 more sources

Polar Isodistance Curves on Parametric Surfaces [PDF]

open access: yes, 2002
In this paper, a new method for interrogation of parametric surfaces is introduced. The basic idea is to consider the distance measured on certain curves on a surface as an interrogation tool. To this aim, two different sets of characteristic curves are considered: the normal section curves and the geodesic curves.
Jaime Puig-Pey   +2 more
openaire   +1 more source

Polar germs, Jacobian ideal and analytic classification of irreducible plane curve singularities [PDF]

open access: yes
We examine the relationship between the analytic type of an irreducible plane curve singularity with a single characteristic exponent and the germs of curve defined by the elements of its Jacobian ideal, in particular its polar ...
Casas Alvero, Eduardo
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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