Results 121 to 130 of about 314,270 (307)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Variation in summer nitrogen and phosphorus uptake among Siberian headwater streams

, 2016
Arctic streams are likely to receive increased inputs of dissolved nutrients and organic matter from thawing permafrost as climate warms. Documenting how Arctic streams process inorganic nutrients is necessary to understand mechanisms that regulate ...
Frey, Karen E., Zimov, Nikita, Seth Spawn, Robert M. Holmes, Schade, John D., William V. Sobczak, John D. Schade, Holmes, Robert M., Erin C. Seybold, Drake, Travis, Sobczak, William V., Spawn, Seth, Nikita Zimov, Travis Drake, Seybold, Erin C., Karen E. Frey   +15 more
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Large unconventional anomalous Hall effect far above room temperature in epitaxial Fe3Ga4 films

npj Quantum Materials
Noncoplanar spin textures usually exhibit a finite scalar spin chirality (SSC) that can generate effective magnetic fields and lead to additional contributions to the Hall effect, namely topological or unconventional anomalous Hall effect (UAHE).
Jing Meng, Huali Yang, Yu Shen, Kun Zheng, Hongru Wang, Yuhao Wang, Keqi Xia, Bocheng Yu, Xiaoyan Zhu, Baiqing Lv, Yaobo Huang, Jie Ma, Dariusz Jakub Gawryluk, Toni Shiroka, Zhenzhong Yang, Yang Xu, Qingfeng Zhan, Tian Shang   +17 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

In-memory ferroelectric differentiator

Nature Communications
Differential calculus is the cornerstone of many disciplines, spanning the breadth of modern mathematics, physics, computer science, and engineering. Its applications are fundamental to theoretical progress and practical solutions.
Guangdi Feng, Xiaoming Zhao, Xiaoyue Huang, Xiaoxu Zhang, Yangyang Wang, Wei Li, Luqiu Chen, Shenglan Hao, Qiuxiang Zhu, Yachin Ivry, Brahim Dkhil, Bobo Tian, Peng Zhou, Junhao Chu, Chungang Duan   +14 more
doaj   +1 more source

ECAPD9 - 9th European Conference on Application of Polar Dielectrics

, 2008
The 9th European Conference on Applications of Polar Dielectrics (ECAPD) will be held in Roma, Italy, from tuesday August 26th to friday August 29th 2008. ECAPD is the principal european and international forum where the latest research and technological
BERTOLOTTI, Mario, MICHELOTTI, Francesco
core  

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source