Results 61 to 70 of about 380,733 (291)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Climate‐Induced Polar Motion: 1900–2100

Geophysical Research Letters
It has been demonstrated that the motion of the Earth's rotational pole with respect to the crust—termed polar motion—is increasingly influenced by barystatic processes, that is, continental‐ocean mass redistribution due to melting of polar ice sheets ...
Mostafa Kiani Shahvandi, Benedikt Soja
doaj   +1 more source

Integral dose during constant velocity motion near a space power reactor [PDF]

, 1972
The dose rate in a rotationally-symmetric radiation field near a space power reactor is assumed to be inversely proportional to separation distance squared and directly proportional either to a constant or a constant times the sine-cubed of a polar angle.
Manning, H. S.
core   +2 more sources

Seasonal excitation of polar motion

Journal of Geodynamics, 2012
We estimate geophysical excitations (chi(1) and chi(2)) of polar motion using multiple sources of data, including recent atmospheric, oceanic, and hydrological models, satellite gravity measurements from the Gravity Recovery and Climate Experiment (GRACE), and compare geophysical excitations with observed polar motion excitations from space geodetic ...
Chen, J., Wilson, C., Zhou, Y.
openaire   +3 more sources

Excitation of Mars polar motion [PDF]

Astronomy & Astrophysics, 2006
In this paper, computations of Mars' polar motion are presented for Mars models with three homogeneous layers as a function of the radius of the inner core and for different excitation possibilities (atmosphere, ice caps, quakes). We estimated the amplitude of the two polar motion normal modes, i.e.
Dehant, Véronique, de Viron, O., Karatekin, O., Van Hoolst, T.   +3 more
openaire   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Signatures of the Martian rotation parameters in the Doppler and range observables

, 2017
The position of a Martian lander is affected by different aspects of Mars' rotational motions: the nutations, the precession, the length-of-day variations and the polar motion.
Dehant, Veronique, Peters, Marie-Julie, Yseboodt, Marie   +2 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Curvature-controlled defect dynamics in active systems

, 2017
We have studied the collective motion of polar active particles confined to ellipsoidal surfaces. The geometric constraints lead to the formation of vortices that encircle surface points of constant curvature (umbilics).
Dunlop, John W. C., Ehrig, Sebastian, Ferracci, Jonathan, Weinkamer, Richard   +3 more
core   +1 more source