Results 51 to 60 of about 61,418 (298)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Atmospheric excitation of polar motion [PDF]
, 1996 Analysis of nonseasonal polar motion excitation and atmospheric mass equatorial angular momentum (EAM) over land for the period 1980-1993 reveals a clear pattern of high power and correlation during the northern hemisphere (NH) winter followed by low ...
Kuehne, John William, 1960-
core +1 more source
Earth and Space ScienceGrowing interest in Earth Orientation Parameters (EOP) resulted in various approaches to the EOP prediction algorithms, as well as in the exploitation of distinct input data, including the observed EOP values from various operational data centers and ...
Tomasz Kur +50 more
doaj +1 more source
Geodynamics of the Wadati-Benioff zone earthquakes: The 2004 Sumatra earthquake and other great earthquakes [PDF]
Geofísica Internacional, 2007 The displacement of the Earth’s instantaneous rotation pole – observed at ASI of Matera, Italy – the seismic data (USGS) in the two days following the main shock, the high frequency P-wave radiation, the geomorphologic data, and the satellite data of ...
Giancarlo Scalera
doaj
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Long term components in polar motion
Annals of Geophysics, 1972 The analysis of a long series of l a t i t u d e observations carried<br />out in t h e International Latitude Station has allowed a very careful study<br />of forced motion due to meteorological effects and of t h e remaining motion<br ...
E. PROVERBIO, V. QUESADA
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Research on Earth rotation and geodynamics in Poland in 2015–2018 [PDF]
Geodesy and Cartography, 2019 This paper summarizes the activity of the chosen Polish geodetic research teams in 2015–2018 in the fields of Earth: rotation, dynamics as well as magnetic field.
Janusz Bogusz +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Estimation of the Parameters of the Earth's Polar Motion [PDF]
Symposium - International Astronomical Union, 1979 The parameters of the Earth's polar motion have been estimated by a method which accounts for observational error and which treats two possible statistical models for the polar motion excitation process. Both a 100 year and a 78 year long polar motion series have been used to estimate the Chandler wobble frequency, Fc, and quality factor, Qc; the noise
openaire +1 more source