Results 61 to 70 of about 1,547,748 (299)
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
The Chief Editor welcomes you to a free, green Polar Research
, 2010 Polar Research is now an open-access journal, freely available to anyone with a computer and connection to the internet. Now readers around the world will have free access to the latest scientific articles on climate, biodiversity, polar history and ...
Goldman, Helle
core +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Remote Sensing, 2019 Sentinel-3A/3B (S3A/B) satellites are equipped with a number of precise instruments dedicated to the measurement of surface topography, sea and land surface temperatures and ocean and land surface color.
Dariusz Strugarek +6 more
doaj +1 more source
Origin of polar order in dense suspensions of phototactic micro-swimmers. [PDF]
PLoS ONE, 2012 A main question for the study of collective motion in living organisms is the origin of orientational polar order, i.e., how organisms align and what are the benefits of such collective behaviour. In the case of micro-organisms swimming at a low Reynolds
Silvano Furlan +5 more
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Co-seismic Earth’s rotation change caused by the 2012 Sumatra earthquake
Geodesy and Geodynamics, 2012 Earthquakes heavily deform the crust in the vicinity of the fault, which leads to mass redistribution in the earth interior. Then it will produce the change of the Earth’s rotation (polar motion and length of day) due to the change of Earth inertial ...
Xu Changyi, Sun Wenke
doaj +1 more source
Climate‐driven polar motion [PDF]
Journal of Geophysical Research: Solid Earth, 1999 The output of a coupled climate system model provides a synthetic climate record with temporal and spatial coverage not attainable with observational data, allowing evaluation of climatic excitation of polar motion on timescales of months to decades. Analysis of the geodetically inferred Chandler excitation power shows that it has fluctuated by up to ...
Michael A. Celaya +2 more
openaire +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Comments to a polar bear population model
, 1985 Larsen, T. & Ugland, K. I. (Polar Research 2 n.s., 117-118) note correctly that a Leslie matrix model treats cubs and females as independent units which is not the case for polar bears.
Øritsland, Nils Are
core +1 more source