Results 51 to 60 of about 1,852,127 (286)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

American Polar Society Symposium 2003 [PDF]

, 2003
Women's Roles in Polar Regions: Past, Present, and Future. American Polar Society Symposium 2003. Byrd Polar Research Center, The Ohio State University, Columbus, Ohio, October 9-10, 2003.Byrd Polar Research Center, The Ohio State UniversityAmerican ...
Byrd Polar Research Center
core   +1 more source

Low‐frequency excitation of length of day and polar motion by the atmosphere [PDF]

Journal of Geophysical Research: Solid Earth, 2004
Results of a 100‐year run of the Hadley Centre general circulation model are used to compute monthly values of the three components of atmospheric torque on the Earth and of the associated atmospheric angular momentum series. All these results are compared with equivalent ones from the National Center for Environmental Prediction/National Center for ...
de Viron, Olivier, Salstein, David, Bizouard, Christian, Fernandez, Laura   +3 more
openaire   +3 more sources

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Study on sloshing simulation in the independent tank for an ice-breaking LNG carrier

International Journal of Naval Architecture and Ocean Engineering, 2020
As the LNG carrier operates in ice covered waters, it is key to ensure the overall safety, which is related to the coupling effect of ice-breaking process and internal liquid sloshing. This paper focuses on the sloshing simulation of the ice-breaking LNG
Shifeng Ding, Gang Wang, Qiuming Luo
doaj   +1 more source

Preliminary study on hydrological angular momentum determined from CMIP6 historical simulations

Earth, Planets and Space, 2022
Polar motion (PM) is an essential parameter needed to transform coordinates between celestial and terrestrial reference frames, thus playing a crucial role in precise positioning and navigation.
Jolanta Nastula, Justyna Śliwińska, Tomasz Kur, Małgorzata Wińska, Aleksander Partyka   +4 more
doaj   +1 more source

Long‐term polar motion excited by ocean thermal expansion [PDF]

Geophysical Research Letters, 2009
Ocean warming is commonly considered unable to excite significant long‐term trends in polar motion. Here, however, we argue that this assumption needs to be revised. We demonstrate that steric sea level rise leads to a distinct pattern of horizontal mass redistribution within ocean basins and hence to ocean bottom pressure changes that alter Earth's ...
Landerer, F., Jungclaus, J. ; https://orcid.org/0000-0002-3849-4339, Marotzke, J.   +2 more
openaire   +2 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

On Some Natures of the Excitation and Damping of the Polar Motion [PDF]

Symposium - International Astronomical Union, 1972
Values of the Chandlerian period and the damping coefficient of the polar motion are calculated for every ten years from 1900.0 to 1970.0, using a method developed by Sekiguchi (1966). The damping coefficient is variable between 0.074 and 0.008 (yr)−1 through this period, and correlative with the variation of the Chandlerian period, as Sekiguchi (1961)
openaire   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source