Results 51 to 60 of about 538,294 (297)

Adding value to extended-range forecasts in northern Europe by statistical post-processing using stratospheric observations [PDF]

Atmospheric Chemistry and Physics, 2020
The strength of the stratospheric polar vortex influences the surface weather in the Northern Hemisphere in winter; a weaker (stronger) than average stratospheric polar vortex is connected to negative (positive) Arctic Oscillation (AO) and colder (warmer)
N. Korhonen, O. Hyvärinen, M. Kämäräinen, D. S. Richardson, H. Järvinen, H. Gregow   +5 more
doaj   +1 more source

Vortex erosion in a shallow water model of the polar vortex

Dynamics of Atmospheres and Oceans, 2017
Abstract The erosion of a model stratospheric polar vortex in response to bottom boundary forcing is investigated numerically. Stripping of filaments of air from the polar vortex has been implicated in the occurrence of stratospheric sudden warmings (SSWs) but it is not understood in detail what factors determine the rate and amount of stripping ...
Beaumont, R, Kwasniok, F, Thuburn, J
openaire   +2 more sources

Multimodel climate and variability of the stratosphere [PDF]

, 2011
The stratospheric climate and variability from simulations of sixteen chemistry‐climate models is evaluated. On average the polar night jet is well reproduced though its variability is less well reproduced with a large spread between models.
T. Nakamura, Garny, Hella, J.-F. Lamarque, H. Teyssèdre, M. Dameris, Hardiman, S. C., Garny, H., S. M. Osprey, Garcia, R., J. Perlwitz, D. Smale, D. Plummer, Haynes, P.H., J. Pyle, E. Rozanov, Akiyoshi, H., Charlton-Perez, A., Morgenstern, O., M. Marchand, Y. Yamashita, Lamarque, J. F., Braesicke, P., Brühl, C., Baumgaertner, A., Kushner, P., Dameris, Martin, Kushner, P. J., Chipperfield, M., Butchart, Neal, Wang, L., M. Sigmond, Tian, W., Perlwitz, J., Osprey, S. M., H. Akiyoshi, R. Garcia, V. Eyring, K. Krüger, Bekki, S., Eyring, V., A. Baumgaertner, Jöckel, P., Osprey, S., et, al., P. H. Haynes, M. Michou, S. Bekki, Newman, P. A., Shepherd, T. G., Krüger, Kirstin, Eyring, Veronika, Butchart, N., D. Waugh, Haynes, P. H., Rozanov, E., Pawson, S., Lamarque, J.-F., Charlton-Perez, A. J., J. Austin, Smale, D., Austin, J., Michou, M., Marchand, M., Newman, P., Hardiman, S., Waugh, D., Cionni, Irene, J. Scinocca, A. J. Charlton-Perez, P. J. Kushner, S. C. Hardiman, Smale, Dan, Marchand, Marion, K. Shibata, H. Garny, S. Pawson, Cionni, I., Sigmond, M., T. G. Shepherd, C. Brühl, S. Dhomse, P. Braesicke, P. A. Newman, Shepherd, T., Scinocca, J., Bekki, Slimane, M. Chipperfield, I. Cionni, Plummer, D., Dameris, M., Morgenstern, Olaf, N. Butchart, Lamarque, J., Dhomse, S., Yamashita, Y., Haynes, P., P. Jöckel, Pyle, J., Teyssèdre, H., L. Wang, O. Morgenstern, Charlton-Perez, Andrew J., Newman, P.A., Krüger, K., W. Tian, Shibata, K., Hardiman, S.C., Charlton-Perez, A.J., Jöckel, Patrick, Osprey, S.M., Nakamura, T., Michou, Martine   +111 more
core   +2 more sources

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

A vortex dynamics perspective on stratospheric sudden warmings [PDF]

, 2009
A vortex dynamics approach is used to study the underlying mechanisms leading to polar vortex breakdown during stratospheric sudden warmings (SSWs).
Matthewman, N.J.
core  

Antarctic polar vortex dynamics in 2019 and 2020 under the influence of the subtropical stratosphere [PDF]

, 2023
The trend of strengthening of the Antarctic polar vortex in late spring and early summer (November–December) has been observed in recent decades. A good example of this trend is the dynamics of the Antarctic polar vortex in 2020 when it existed until the
E. S. Savelieva, E. A. Maslennikova, O. G. Chkhetiani, V. N. Krupchatnikov, V. V. Zuev, I. V. Borovko, A. V. Pavlinsky   +6 more
core   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Polarization conversion when focusing cylindrically polarized vortex beams [PDF]

Scientific Reports, 2016
AbstractCurrently, cylindrical beams with radial or azimuthal polarization are being used successfully for the optical manipulation of micro- and nano-particles as well as in microscopy, lithography, nonlinear optics, materials processing, and telecommunication applications.
Alexey P. Porfirev, Andrey V. Ustinov, Svetlana N. Khonina   +2 more
openaire   +3 more sources

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source