Results 81 to 90 of about 245,756 (303)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Machine learning-based tumor associated macrophages polarity signature predicts prognosis and treatment response in hepatocellular carcinoma

Frontiers in Immunology
BackgroundTumor-associated macrophages (TAMs) shape the tumor microenvironment and drive hepatocellular carcinoma (HCC) progression. However, the prognostic significance of TAM polarity-related genes, particularly based on the CXCL9:SPP1 signature ...
Fangzhou Wang, Quan Zhang, Shichun Lu, Yamin Zheng   +3 more
doaj   +1 more source

A study of high proper-motion white dwarfs I. Spectropolarimetry of a cool hydrogen-rich sample

, 2012
We conducted a spectropolarimetic survey of 58 high proper-motion white dwarfs which achieved uncertainties of >2 kG in the Halpha line and >5 kG in the upper Balmer line series.
Adéla Kawka, Aurière, Aznar Cuadrado, Bagnulo, Barstow, Benvenuto, Bergeron, Bergeron, Brinkworth, Burleigh, Carollo, Carrier, Chiba, Costa, Dobbie, Dufour, Eggen, Eggen, Eggen, Fabrika, Farihi, Ferrario, Garcés, García-Berro, Garstang, Giammichele, Gianninas, Girardi, Girven, Gould, Greenstein, Hintzen, Johnson, Jordan, Jordan, Kalirai, Kawka, Kawka, Kawka, Kawka, Kawka, Kawka, Kawka, Kawka, Kawka, Kemic, Kepler, Kilic, Kilic, Kilkenny, Kleinman, Koester, Koester, Kowalski, Lamontagne, Limoges, Luyten, Luyten, Lépine, Lépine, Martin, Maxted, Maxted, McCook, Muslimov, Nordhaus, Oppenheimer, Patat, Pauli, Pokorny, Potter, Putney, Reid, Salim, Salim, Schaller, Schilbach, Schmidt, Schmidt, Schmidt, Serenelli, Silvestri, Skrutskie, Smith, Stéphane Vennes, Subasavage, Subasavage, Tout, Tremblay, Valyavin, van Leeuwen, Vennes, Vennes, Vennes, Vergely, Welsh, Wesemael, Wickramasinghe, Zuckerman, Zuckerman   +99 more
core   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Direct Metal Deposition of Graphene–Ti28Nb35.4Zr Matrix Composites With Enhanced Mechanical, Corrosion, and Biocompatibility Properties for Bone Implants

Advanced Engineering Materials, EarlyView.
Graphene nanoplatelet (0.1 wt.%) reinforcement significantly enhances the performance of β Ti‐28Nb‐35.4Zr alloy. Grain refinement, reduced water contact angle, and improved surface characteristics promote osteoblast adhesion and complete surface coverage after 7 days.
Khurram Munir, Jixing Lin, Yuncang Li, Li Zhu, Paul F. A. Wright, Cuie Wen   +5 more
wiley   +1 more source

Single-Run Separation of Closely Related Cationic and Anionic Compounds by CE-ESI-MS: Application to the Simultaneous Analysis of Melamine and its Analogs in Milk

CHIMIA, 2011
In recent years, two adulteration incidents concerning the addition of melamine, a nitrogen-rich-industrial small polar compound, to pet food and infant formula products have occurred in China.
Isabelle Kohler, Emmanuelle Cognard, Ivano Marchi, Didier Ortelli, Patrick Edder, Jean-Luc Veuthey, Serge Rudaz, Julie Schappler   +7 more
doaj   +1 more source

An Experimental High‐Throughput Approach for the Screening of Hard Magnet Materials

Advanced Engineering Materials, EarlyView.
An entire workflow for the high‐throughput characterization and analysis of compositionally graded magnetic films is presented. Characterization protocols, data management tools and data analysis approaches are illustrated with test case Sm(Fe, V)12 based films.
William Rigaut, Pierre Le Berre, Hamdi Jaballah, Lukas Fink, Victor Poline, Richard Haettel, Stéphane Grenier, Gilbert Chahine, Ewen Bellec, Guillaume Buatier, Wilfried Hortschitz, Santa Pile, Thomas Schrefl, Nils Blanc, Yuan Hong, Thibaut Devillers, Nora M. Dempsey   +16 more
wiley   +1 more source

Optimized PAR-2 RING dimerization mediates cooperative and selective membrane binding for robust cell polarity

The EMBO Journal
Cell polarity networks are defined by quantitative features of their constituent feedback circuits, which must be tuned to enable robust and stable polarization, while also ensuring that networks remain responsive to dynamically changing cellular states ...
Tom Bland, Nisha Hirani, David C Briggs, Riccardo Rossetto, KangBo Ng, Ian A Taylor, Neil Q McDonald, David Zwicker, Nathan W Goehring   +8 more
doaj   +1 more source

Negative Dependencies in Turkish

Languages
In this paper, we provide an overview of negative dependencies in Turkish. The first are elements such as hiçkimse, which sometimes seem to mean ‘anybody’ and sometimes ‘nobody’.
Beste Kamali, Hedde Zeijlstra
doaj   +1 more source

Photoswitchable Conductive Metal–Organic Frameworks

Advanced Functional Materials, EarlyView.
A conductive material where the conductivity can be modulated remotely by irradiation with light is presented. It is based on films of conductive metal–organic framework type Cu3(HHTP)2 with embedded photochromic molecules such as azobenzene, diarylethene, spiropyran, and hexaarylbiimidazole in the pores.
Yidong Liu, Mersad Mostaghimi, Abhinav Chandresh, Saibal Jana, Wolfgang Wenzel, Lars Heinke   +5 more
wiley   +1 more source