Results 71 to 80 of about 779,144 (306)
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Generation and characterization of polarization scrambled optical signals [PDF]
, 2012 Controlling the state of polarization of a light beam of an optical fiber is of crucial importance. Non-Linear Polarization Pulling (NLPP) is an all-optical way to control the state of polarization of signals which has been proposed in recent years ...
Pegoraro, Alex
core
Annals of Pure and Applied Logic, 2003 We generalize the intuitionistic Hyland-Ong games to a notion of polarized games allowing games with plays starting by proponent moves. The usual constructions on games are adjusted to fit this setting yielding a game model for polarized linear logic with a definability result.
openaire +4 more sources
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Effect of oceanic turbulence on the statistical features of electromagnetic optical beam
Results in PhysicsThis work deals with the intricate problem of electromagnetic optical beam propagation through oceanic turbulence. Using the extended Huygens–Fresnel principle, numerically, the behavior of the degree of cross-polarization (DOCP), electromagnetic degree ...
Hemant Kumar Singh +2 more
doaj +1 more source
Cell polarity: Par for the polar course [PDF]
Current Biology, 1997 The nematode PAR-1 gene is required for asymmetric cell divisions during development. Recently identified mammalian Par-1 homologues are kinases that phosphorylate microtubule-associated proteins; their overexpression disrupts the microtubule cytoskeleton, and alters cellular structure and organization.
Nelson, W.James, Grindstaff, Kent K.
openaire +2 more sources
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Interleaved Polar (I-Polar) Codes [PDF]
IEEE Transactions on Information Theory, 2020 31 pages, 12 ...
openaire +4 more sources
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source