Results 61 to 70 of about 779,144 (306)

Comparative Study of Modified Mueller Matrix Transformation and Polar Decomposition Parameters for Transmission and Backscattering Tissue Polarimetries

open access: yesApplied Sciences, 2021
Mueller matrix polarimetry is widely used in biomedical studies and applications, for it can provide abundant microstructural information about tissues.
Binguo Chen   +6 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Four-zone reflective polarization conversion plate [PDF]

open access: yes, 2014
The work was partially funded by the Russian Foundation Basic Research grants ## 13-07-97008, 14-07-31092, and 14-07-97039, the Russian Federation Presidential grant for state support of young Russian scientists with Candidate's degree MK-4816.2014.2 ...
L. O'Faolain   +7 more
core   +1 more source

Polarimetry feature parameter deriving from Mueller matrix imaging and auto-diagnostic significance to distinguish HSIL and CSCC

open access: yesJournal of Innovative Optical Health Sciences, 2022
High-grade squamous intraepithelial lesion (HSIL) is regarded as a serious precancerous state of cervix, and it is easy to progress into cervical invasive carcinoma which highlights the importance of earlier diagnosis and treatment of cervical lesions ...
Anli Hou   +7 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Scalable, tailored purity heralded single-photon source enabled by second harmonic generation of GHz-rate ultrashort pulsed laser [PDF]

open access: yesAPL Quantum
We demonstrate a miniaturized, scalable high rate, pulsed single-photon source in the telecom band obtained by heralding a spontaneous parametric downconversion source pumped with a highly tunable GHz repetition rate pulsed laser in an all-guided wave ...
Sangeeta, Bhaskar Kanseri
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

One-step growth method of silver nanowires in aqueous environment

open access: yesMaterials Research Express, 2020
Silver nanowires were successfully prepared by one-step growth method in aqueous environment. The suitable pH value is a key factor for the successful preparation of silver nanowires.
Xiao-Li Liu   +6 more
doaj   +1 more source

Cell Polarity: The importance of being polar [PDF]

open access: yesCurrent Biology, 1995
Cell polarization is often accompanied by cytoskeletal rearrangements. Two signalling proteins, a GTPase and a kinase, are required for both actin and microtubule rearrangements. Are these two systems coupled?
Glotzer, Michael, Hyman, Anthony A.
openaire   +2 more sources

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