Results 61 to 70 of about 810,570 (309)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Polarization-Shaped Strong Field Control over Valley Polarization with Mid-IR Light
, 2022 We induce control over valley polarization with a polarization-shaped mid-infrared light field. The polarization state of the trefoil-shaped pump fields is measured by high harmonic spectroscopy, which we also use to confirm strong field control over non-
Mikhail Ivanov (3447290) +6 more
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Journal of Innovative Optical Health Sciences, 2022 High-grade squamous intraepithelial lesion (HSIL) is regarded as a serious precancerous state of cervix, and it is easy to progress into cervical invasive carcinoma which highlights the importance of earlier diagnosis and treatment of cervical lesions ...
Anli Hou +7 more
doaj +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Scalable, tailored purity heralded single-photon source enabled by second harmonic generation of GHz-rate ultrashort pulsed laser [PDF]
APL QuantumWe demonstrate a miniaturized, scalable high rate, pulsed single-photon source in the telecom band obtained by heralding a spontaneous parametric downconversion source pumped with a highly tunable GHz repetition rate pulsed laser in an all-guided wave ...
Sangeeta, Bhaskar Kanseri
doaj +1 more source
One-step growth method of silver nanowires in aqueous environment
Materials Research Express, 2020 Silver nanowires were successfully prepared by one-step growth method in aqueous environment. The suitable pH value is a key factor for the successful preparation of silver nanowires.
Xiao-Li Liu +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Cell Polarity: The importance of being polar [PDF]
Current Biology, 1995 Cell polarization is often accompanied by cytoskeletal rearrangements. Two signalling proteins, a GTPase and a kinase, are required for both actin and microtubule rearrangements. Are these two systems coupled?
Glotzer, Michael, Hyman, Anthony A.
openaire +2 more sources