Results 101 to 110 of about 20,155 (297)

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

Advanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang, Shanshan Huang, Yong Wang, Zhiwen Jiang, Zhuohang Liu, Chenran Wang, Rong Ji, Yiwen Yuan, Xueyu Mao, Kaicheng Yang, Huicong Niu, Yanqin Gao, Jing Zhao   +12 more
wiley   +1 more source

Dataset for Spatial and polarization division multiplexing harnessing on-chip optical beam forming

, 2023
David González‐Andrade, Xavier Le Roux, Guy Aubin, Farah Amar, Thi Hao Nhi Nguyen, Paula Nuño Ruano, Thi Thuy Duong Dinh, Dorian Oser, Diego Pérez‐Galacho, Éric Cassan, Delphine Marris‐Morini, Laurent Vivien, Carlos Alonso‐Ramos   +12 more
openalex   +1 more source

Mode and Polarization‐Division Multiplexing Based on Silicon Nitride Loaded Lithium Niobate on Insulator Platform (Laser Photonics Rev. 16(1)/2022) [PDF]

, 2022
Xu Han, Yongheng Jiang, Andreas Frigg, Huifu Xiao, Pu Zhang, Thach G. Nguyen, Andreas Boes, Jianhong Yang, Guanghui Ren, Yikai Su, Arnan Mitchell, Yonghui Tian   +11 more
openalex   +1 more source

IL4I1⁺ Macrophages and TDO2⁺ Myofibroblasts Drive AhR‐Mediated Immunosuppression and Ferroptosis Resistance in Solid Predominant Lung Adenocarcinoma

Advanced Science, EarlyView.
Solid predominant lung adenocarcinoma exhibits an immune‐excluded, ferroptosis‐resistant niche enriched with IL4I1⁺ TAMs and TDO2⁺ myCAFs. Spatial and multi‐omics analyses reveal AhR‐driven crosstalk that promotes T cell exhaustion and therapy resistance. Blocking AhR with CH‐223191 restores ferroptosis sensitivity, and its combination with ferroptosis
Zhaoxuan Wang, Weijiao Xu, Lei Zhao, Lin Zhong, Wendan Yu, Shengmin Wang, Lu Sun, Tao Guo, Fengzhou Li, Zhuoshi Li, Lei Fang, Shiqing Wang, Guohui Zhang, Guoqing Xue, Wei Guo, Shilei Zhao, Chundong Gu   +16 more
wiley   +1 more source

Achieving Large Multiplexing Gain in Distributed Antenna Systems via Cooperation with pCell Technology

, 2016
In this paper we present pCellTM technology, the first commercial-grade wireless system that employs cooperation between distributed transceiver stations to create concurrent data links to multiple users in the same spectrum.
Caire, Giuseppe, Di Dio, Mario, Forenza, Antonio, Perlman, Stephen, Saibi, Fadi, van der Laan, Roger   +5 more
core   +1 more source

Linearly polarized vector modes: enabling MIMO-free mode-division multiplexing

Optics Express, 2017
We experimentally investigate mode-division multiplexing in an elliptical ring core fiber (ERCF) that supports linearly polarized vector modes (LPV). Characterization show that the ERCF exhibits good polarization maintaining properties over eight LPV modes with effective index difference larger than 1 × 10-4. The ERCF further displays stable mode power
Lixian, Wang, Reza Mirzaei, Nejad, Alessandro, Corsi, Jiachuan, Lin, Younès, Messaddeq, Leslie, Rusch, Sophie, LaRochelle   +6 more
openaire   +2 more sources

Loss of SOCS1 in Donor T Cells Exacerbates Intestinal GVHD by Driving a Chemokine‐Dependent Pro‐Inflammatory Immune Microenvironment

Advanced Science, EarlyView.
T cell‐specific Socs1 knockout leads to inflammatory differentiation of CD8+ T cells, prompting the STAT1/2 complex to drive the activation of Ccl5, Ccr5, and Cxcr3, and promoting the skewing of monocytes toward a pro‐inflammatory M1 macrophage lineage.
Zhigui Wu, Bixia Wang, Xinya Jiang, Fangqing Zhang, Qianqian Huang, Xinyi Wu, Shuang Fan, Qi Zhang, Jingrui Zhou, Jianing Tang, Xiao‐Dong Mo, Yu Wang, Ying‐Jun Chang, Huidong Guo, Xiao‐Jun Huang   +14 more
wiley   +1 more source

Sub-Nyquist Field Trial Using Time Frequency Packed DP-QPSK Super-Channel Within Fixed ITU-T Grid

, 2015
Sub-Nyquist time frequency packing technique was demonstrated for the first time in a super channel field trial transmission over long-haul distances. The technique allows a limited spectral occupancy even with low order modulation formats.
Berrettini, G., Cavaliere, F., Foggi, T., Forgan, R., Fresi, F., Giorgi, L., Hackett, S., Leong, A., Masciulli, R., Meloni, G., Nibbs, P., Petronio, A., Pfander, C., Potì, L., Secondini, M.   +14 more
core   +1 more source

Single‐Cell Profiling Across Immune Tissues and Organs Reveals Immunosenescence Signatures in Male Rhesus Monkeys

Advanced Science, EarlyView.
Single‐cell profiling across bone marrow, spleen, mesenteric lymph, and blood in rhesus monkeys reveals organ Immunosenescence. GZMB rises with age, particularly in cytotoxic and terminally exhausted CD8+ T cells, and BHLHE40 emerges as a key transcription factor enriched across multiple CD8+ subsets, regulating pro‐inflammatory and exhaustion‐related ...
Shengnan Wang, Zhengna Zhu, Hongju Yang, Yaping Yan, Luyao Ran, Naixue Yang, Yichao Wang, Li Wu, Bing Bai, Weizhi Ji, Wei Si   +10 more
wiley   +1 more source

Over 100 Gb/s Ultrabroadband MIMO Wireless Signal Delivery System at the D-Band

IEEE Photonics Journal, 2016
We propose and experimentally demonstrate an ultrabroadband wireless millimeter-wave (mm-wave) signal delivery system at the D-band (110–170 GHz), employing the techniques of photonics-aided mm-wave generation, wireless multiple-input ...
Xinying Li, Jianjun Yu
doaj   +1 more source