Results 131 to 140 of about 20,155 (297)

Reprogramming M2b Macrophages via GPX1 Activation by Selenium Nanoparticles Attenuates Lupus Nephritis

open access: yesAdvanced Science, EarlyView.
SeZM NPs selectively target M2b macrophages through mannose–MRC1 (CD206) recognition, enhance GPX1 biosynthesis, and suppress mitochondrial ROS generation, oxidative stress, and JAK–STAT signaling. This dual regulation reduces pro‐inflammatory cytokine release, limits immune cell infiltration and fibrosis, and preserves renal function, providing a ...
Haoran Lv   +16 more
wiley   +1 more source

5G NR sub-THz fiber-wireless integrated systems using polarization multiplexing-multiband technique and self-polarization diversity scheme

open access: yesScientific Reports
Fifth generation (5G) new radio (NR) fiber-wireless integrated systems using polarization multiplexing-multiband technique and self-polarization diversity scheme are successfully implemented.
Ming-Chung Cheng   +9 more
doaj   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu   +7 more
wiley   +1 more source

Genetic Algorithm Optimization for Designing Polarization-Maintaining Few-Mode Fibers with Uniform Doping Profiles

open access: yesPhotonics
To support mode-division multiplexing with reduced inter-modal crosstalk, we propose a novel polarization-maintaining few-mode fiber design with a uniform doping profile and no air holes.
Hao Gu   +5 more
doaj   +1 more source

Multi-wavelength fiber laser with erbium doped zirconia fiber and semiconductor optical amplifier

open access: yes, 2010
Multi-wavelength hybrid fiber lasers are demonstrated in both ring and linear cavities using a fabricated Erbium-doped Zirconia fiber (EDZF) and semiconductor optical amplifier (SOA) as gain media.
Ahmad, H.   +13 more
core  

Non‐Volatile Phase Modulation with Ultralow Energy Consumption Enabled by 2D Ferroelectric/TMD Heterostructures

open access: yesAdvanced Science, EarlyView.
We demonstrate a hybrid WS2/CuInP2S6/graphene heterostructure integrated on a silicon nitride microring resonator for non‐volatile optical phase modulation with ultra‐low energy consumption and low insertion loss. While CIPS alone does not provide efficient optical index modulation, the engineered proposed device structure converts ferroelctric domain ...
Lalit Singh   +10 more
wiley   +1 more source

Dispersive Full‐Channel Jones Matrix Modulation in Elliptical Polarization Bases via a Single‐Layered Metasurface

open access: yesAdvanced Science, EarlyView.
This work presents a dispersive full‐channel Jones matrix modulation strategy using single‐layer metasurface. By synergizing wavelength dispersion engineering with elliptical polarization bases, independent control of four Jones matrix channels is achieved across multiple wavelengths.
Hairong He   +10 more
wiley   +1 more source

Simultaneous Conversion of Polarization and Frequency via Time‐Division‐Multiplexing Metasurfaces

open access: hybrid, 2021
Jin Yang   +6 more
openalex   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

open access: yesAdvanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo   +5 more
wiley   +1 more source

Review of Memristors for In‐Memory Computing and Spiking Neural Networks

open access: yesAdvanced Intelligent Systems, EarlyView.
Memristors uniquely enable energy‐efficient, brain‐inspired computing by acting as both memory and synaptic elements. This review highlights their physical mechanisms, integration in crossbar arrays, and role in spiking neural networks. Key challenges, including variability, relaxation, and stochastic switching, are discussed, alongside emerging ...
Mostafa Shooshtari   +2 more
wiley   +1 more source

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