Results 51 to 60 of about 105,727 (257)

Enhancement in dynamic range for dual-rotating retarder Mueller matrix polarimetry

Journal of Innovative Optical Health Sciences
Mueller matrix polarimetry (MMP) has been proven to be a powerful tool for characterizing the microstructural features of biological samples in biomedical research and clinical diagnostics.
Jiongying Lv, Shuan Yao, Nan Zeng, Caizhong Guan, Honghui He   +4 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Quantifying Influence of Beam Drift on Linear Retardance Measurement in Dual-Rotating Retarder Mueller Matrix Polarimetry

Photonics
Mueller matrix polarimetry is recently attracting more and more attention for its diagnostic potentials. However, for prevalently used division of time Mueller matrix polarimeter based on dual-rotating retarder scheme, beam drift induced by rotating ...
Kaisha Deng, Nan Zeng, Liangyu Deng, Shaoxiong Liu, Hui Ma, Chao He, Honghui He   +6 more
doaj   +1 more source

Polarization-intensity joint imaging for marine target automatic recognition

Geocarto International, 2023
The performance of sole optical imaging device for marine target recognition is degraded by sea fog, sea-glint, and many other disturbing factors. To enhance the ability of target recognition in marine environment, we propose a polarization-intensity ...
Aiqi Zhong, Qiang Fu, Danfei Huang, Jingping Zhu, Huilin Jiang   +4 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Orthogonal polarization spectral imaging

Physiological Research, 2007
The microcirculation plays a crucial role in the interaction between blood and tissues both in physiological and pathophysiological states. Despite its critical role in numerous diseases including diabetes, hypertension, sepsis or multiple organ failure, methods for direct visualization and quantitative assessment of human microcirculation at the ...
V, Cerný, Z, Turek, R, Pařízková
openaire   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Imaging the polarization of a light field

Optics Express, 2013
We describe and analyze a method by which an optical polarization state is mapped to an image sensor. When placed in a Bayesian framework, the analysis allows a priori information about the polarization state to be introduced into the measurement.
Roshita D, Ramkhalawon, Thomas G, Brown, Miguel A, Alonso   +2 more
openaire   +2 more sources