Results 61 to 70 of about 2,216,660 (308)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Enhancement in dynamic range for dual-rotating retarder Mueller matrix polarimetry

open access: yesJournal of Innovative Optical Health Sciences
Mueller matrix polarimetry (MMP) has been proven to be a powerful tool for characterizing the microstructural features of biological samples in biomedical research and clinical diagnostics.
Jiongying Lv   +4 more
doaj   +1 more source

Polarization-enabled Multidimensional Optical Microscopy

open access: yes, 2019
Polarization-dependence provides a unique handle for extending the dimensionality of optical microscopy, with particular benefits in nonlinear optical imaging.
Changqin Ding (6331859), Ding, Changqin
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Measured and simulated performance of a ceramic micromechanical beam steering device at 94 GHz [PDF]

open access: yes, 2008
We report the first experimental demonstration of a transmission-mode micromechanical beam steering device for use in standoff terahertz imaging and spectroscopy.
Drysdale, T.D.   +5 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Imaging Polarization in Budding Yeast [PDF]

open access: yes, 2016
We describe methods for live-cell imaging of yeast cells that we have exploited to image yeast polarity establishment. As a rare event occurring on a fast time-scale, imaging polarization involves a trade-off between spatiotemporal resolution and long-term imaging without excessive phototoxicity.
McClure, Allison W   +3 more
openaire   +2 more sources

Terahertz polarization imaging with birefringent materials

open access: yes, 2010
We present a terahertz (THz) imaging method with a birefringent material which is sensitive to THz wave polarization The subtle THz polarization modulations introduced by the target are extracted by the amplitudes of the two separated THz peaks passing ...
Zhao, YueJin   +9 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Quantifying Influence of Beam Drift on Linear Retardance Measurement in Dual-Rotating Retarder Mueller Matrix Polarimetry

open access: yesPhotonics
Mueller matrix polarimetry is recently attracting more and more attention for its diagnostic potentials. However, for prevalently used division of time Mueller matrix polarimeter based on dual-rotating retarder scheme, beam drift induced by rotating ...
Kaisha Deng   +6 more
doaj   +1 more source

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