Results 61 to 70 of about 2,343,049 (308)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Multimodal polarization-resolved/fluorescence optical scanning microscopy for chromatin organization imaging

open access: yes, 2021
We demonstrate a combination of polarization-resolved with fluorescence optical scanning microscopy that offers polarizing based information along with molecular view of sample as a versatile tool for imaging the chromatin ...
Callegari F.   +4 more
core   +1 more source

Enhancement in dynamic range for dual-rotating retarder Mueller matrix polarimetry

open access: yesJournal of Innovative Optical Health Sciences
Mueller matrix polarimetry (MMP) has been proven to be a powerful tool for characterizing the microstructural features of biological samples in biomedical research and clinical diagnostics.
Jiongying Lv   +4 more
doaj   +1 more source

Lensless polarization camera for single-shot full-Stokes imaging

open access: yesAPL Photonics, 2022
Lensless cameras have recently emerged as a compact imaging system based on computational imaging with various multiplexing capabilities. Here, we propose a compact, low-cost, lensless camera that enables snapshot full-Stokes polarization imaging.
Nakkyu Baek   +4 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Imaging Polarization in Budding Yeast [PDF]

open access: yes, 2016
We describe methods for live-cell imaging of yeast cells that we have exploited to image yeast polarity establishment. As a rare event occurring on a fast time-scale, imaging polarization involves a trade-off between spatiotemporal resolution and long-term imaging without excessive phototoxicity.
McClure, Allison W   +3 more
openaire   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Polarization-Sensitive Imaging in Magnetic Environments

open access: yes
Data and code for the figures in the article "Polarization-Sensitive Imaging in Magnetic ...
Nejc Blaznik (Utrecht University)
core   +1 more source

Polarization-dependent imaging with metalenses

open access: yes, 2020
Video showing the evolution of images formed by metalenses as the incident polarization basis ...
Mitsumasa Nakajima (6528104)   +2 more
core   +1 more source

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