Results 51 to 60 of about 1,132,543 (299)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

open access: yesFEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini   +3 more
wiley   +1 more source

Boat

open access: yes, 1940
The launch 'Sea Dog' unloading provisions after the wet - replacement supplies which the shipwrecked boat Chas Pole was on failed to deliver.
Pole, Charlie
core   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Strain rate and microtexture analysis of rapid-quenched AA6061 friction stir welds produced with tool eccentricity

open access: yesJournal of Materials Research and Technology, 2022
The paper investigates the effect of tool eccentricity on the strain rate and microtextures produced in rapid-quenched AA6061 friction stir welds. Thermocouples are embedded in the tool and the thermal cycle are recorded via a data acquisition system ...
Luqman Hakim Ahmad Shah   +4 more
doaj   +1 more source

Practical applications of the method of generalized pole figures [PDF]

open access: yesIOP Conference Series: Materials Science and Engineering, 2015
Several actual practical applications of the new X-ray method of generalized pole figures are considered. Among them there are determination of c- and a-dislocation densities in shell tubes from Zr-1%Nb alloy, analysis of strain hardening at opposite sides of shell tubes from ferrritic-martensitic steel with oxide disperse strengthening particles for ...
Yu Perlovich   +4 more
openaire   +1 more source

Robust Pole Assignment via Sylvester Equation Based State Feedback Parametrization [PDF]

open access: yes, 2000
By using a Sylvester equation based parametrization, the minimum norm robust pole assignment problem for linear time-invariant systems is formulated as an unconstrained minimization problem for a suitably chosen cost function.
Varga, Andras
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

SPECIFIC FEATURES OF DEFORMATION OF THE CONTINENTAL AND OCEANIC LITHOSPHERE AS A RESULT OF THE EARTH CORE NORTHERN DRIFT

open access: yesГеодинамика и тектонофизика, 2015
Drifting and submeridional compression of the continental and oceanic lithosphere, both with the northward vector (Figure 1) are revealed at the background of various directions of horizontal displacement combined with deformations of horizontal ...
Mikhail A. Goncharov   +2 more
doaj   +1 more source

Piezoelectric Pole Figure of a Vein Quartz Sample [PDF]

open access: yesTexture, Stress, and Microstructure, 1988
Longitudinal piezoelectric coefficients have been measured on cubic samples and from 150 different orientations on a spherical sample of coarse‐grained vein quartz. The results are consistent with the presence of a piezoelectric fabric. The piezoelectric pole figure of the studied spherical sample demonstrates three distinct patterns of alternatively ...
M. M. Ghomshei   +4 more
openaire   +1 more source

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