Results 51 to 60 of about 1,024,180 (244)

Strain rate and microtexture analysis of rapid-quenched AA6061 friction stir welds produced with tool eccentricity

open access: yesJournal of Materials Research and Technology, 2022
The paper investigates the effect of tool eccentricity on the strain rate and microtextures produced in rapid-quenched AA6061 friction stir welds. Thermocouples are embedded in the tool and the thermal cycle are recorded via a data acquisition system ...
Luqman Hakim Ahmad Shah   +4 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Boat

open access: yes, 1940
The launch 'Sea Dog' unloading provisions after the wet - replacement supplies which the shipwrecked boat Chas Pole was on failed to deliver.
Pole, Charlie
core   +1 more source

SPECIFIC FEATURES OF DEFORMATION OF THE CONTINENTAL AND OCEANIC LITHOSPHERE AS A RESULT OF THE EARTH CORE NORTHERN DRIFT

open access: yesГеодинамика и тектонофизика, 2015
Drifting and submeridional compression of the continental and oceanic lithosphere, both with the northward vector (Figure 1) are revealed at the background of various directions of horizontal displacement combined with deformations of horizontal ...
Mikhail A. Goncharov   +2 more
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Texture analysis of deformation induced martensite in an AISI 301L stainless steel: microtexture and macrotexture aspects

open access: yesMaterials Research, 2009
Experiments have been conducted to study the strain induced transformation from austenite to martensite in a metastable AISI 301LN austenitic stainless steel, deformed by uniaxial tension applied along rolling direction.
Hamilton Ferreira Gomes de Abreu   +3 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Omega transition accompanied by mechanically-induced twinned martensite

open access: yesMaterials Research Express, 2020
We present here an analysis on omega transition process during martensitic transformation. Martensitic transformation occurred during deformation at room temperature, avoiding the influence of auto-tempering on metastable omega phase.
P J Du, Y J Li, R D K Misra, D Wu
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

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