Results 61 to 70 of about 1,049,521 (250)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Texture analysis of deformation induced martensite in an AISI 301L stainless steel: microtexture and macrotexture aspects

open access: yesMaterials Research, 2009
Experiments have been conducted to study the strain induced transformation from austenite to martensite in a metastable AISI 301LN austenitic stainless steel, deformed by uniaxial tension applied along rolling direction.
Hamilton Ferreira Gomes de Abreu   +3 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Omega transition accompanied by mechanically-induced twinned martensite

open access: yesMaterials Research Express, 2020
We present here an analysis on omega transition process during martensitic transformation. Martensitic transformation occurred during deformation at room temperature, avoiding the influence of auto-tempering on metastable omega phase.
P J Du, Y J Li, R D K Misra, D Wu
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Study of EBSD Experiment Parameters Influence on Computation of Polycrystalline Pole Figures and Orientation Distribution Function

open access: yesMATEC Web of Conferences, 2016
Mathematical model for a polycrystalline specimen and EBSD experiment is proposed. As the measurement parameters, the scanning step and the threshold disorientation angle are considered.
Antonova Anastasia O.   +2 more
doaj   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Ultrasonic pole figure for the texture of an aluminum alloy [PDF]

open access: yesApplied Physics Letters, 1987
An approximate method is proposed to calculate the pole figure diagrams based on the elastic anisotropy measured by ultrasonic velocity experiments. An example is taken from the surface texture of rolled plates of aluminum alloy 7075-T651, for which the angular dependence of the Rayleigh wave is measured in the rolling plane and analyzed to obtain the ...
M. Hirao, N. Hara
openaire   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Piezoelectric Pole Figure of a Vein Quartz Sample [PDF]

open access: yesTexture, Stress, and Microstructure, 1988
Longitudinal piezoelectric coefficients have been measured on cubic samples and from 150 different orientations on a spherical sample of coarse‐grained vein quartz. The results are consistent with the presence of a piezoelectric fabric. The piezoelectric pole figure of the studied spherical sample demonstrates three distinct patterns of alternatively ...
M. M. Ghomshei   +4 more
openaire   +1 more source

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