Results 71 to 80 of about 1,024,180 (244)

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Comparison of Ultrasonic Pole Figures Based Upon Ultrasonic Nondestructive Evaluation Method With Pole Figures Based Upon FEPM.

open access: yesTRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series A, 2001
The ultrasonic wave velocities in a polycrystalline aggregate are sensitively influenced by texture changes due to plastic deformation, and their relationship was systematically analyzed by Sayers. According to Sayers's proposed model, it is possible to construct ultrasonic pole figures via the crystallite orientation distribution function (CODF ...
TANG, Shihua, KOBAYASHI, Michiaki
openaire   +2 more sources

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

A numerically reliable approach to robust pole assignment for descriptor systems [PDF]

open access: yes, 2003
We propose a general, numerically reliable computational approach to solve the pole and eigenstructure assignment problem for descriptor systems. In the multi-input case, the proposed approach addresses the intrinsic non-uniqueness of the pole assignment
A. Varga, Varga, Andras
core  

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

Robust and minimum norm pole assignment with periodic state feedback [PDF]

open access: yes, 1998
A computational approach is proposed to solve the minimum norm and/or robust pole assignment problem for linear periodic discrete-time systems. The proposed approach uses a periodic Sylvester equation based parametrization of the periodic pole ...
Varga, A.
core  

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Man with pig

open access: yes, 1940
Mr Turnoff, Evans Deakins (Engineer). Chas Pole was to act as his guide when they arrived at the Daly.
Pole, Charlie
core  

Robust and Minimum Norm Pole Assignment with Periodic State Feedback [PDF]

open access: yes, 2000
A computational approach is proposed to solve the minimum norm or robust pole assignment problem for linear periodic discrete-time systems. The proposed approach uses a periodic Sylvester-equation-based parametrization of the periodic pole assignment ...
Varga, A.
core  

Texture Evolution and Anisotropy of Plastic Flow in Hot Compression of Extruded ZK60-T5 Magnesium Alloy Plate

open access: yesMetals, 2019
The texture evolution during hot compression of extruded ZK60A-T5 magnesium alloy plate loaded along the extrusion direction (ED) and the normal direction (ND) has been examined with the help of pole figures obtained on specimens deformed in the ranges ...
Chalasani Dharmendra   +3 more
doaj   +1 more source

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