Results 31 to 40 of about 687,753 (247)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Numerical methods for calculating poles of the scattering matrix with applications in grating theory

open access: yes, 2012
Waveguide and resonant properties of diffractive structures are often explained through the complex poles of their scattering matrices. Numerical methods for calculating poles of the scattering matrix with applications in grating theory are discussed.
Bykov, Dmitry A., Doskolovich, Leonid L.
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

POLES DANCE

open access: yesArt&Sensorium, 2022
O título para este ensaio visual não pretende ocultar, como pode parecer, nossa preocupação com a questão ambiental em sua dimensão político-planetária. Muito pelo contrário, trata-se de que tal como eu, como artista, a compreendo, não é algo simples como dizer que a natureza está sendo destruída pela ação de tais e quais fatores.
openaire   +2 more sources

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Threshold behavior of scattering poles

open access: yes, 2003
The results of a model for meson-meson scattering are studied. The model is shown to be capable of on the one hand reproducing the scattering data, while on the other hand a quark-antiquark confinement spectrum can be determined.
Rupp, George, van Beveren, Eef
core   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Poles of regular quaternionic functions

open access: yes, 2008
This paper studies the singularities of Cullen-regular functions of one quaternionic variable. The quaternionic Laurent series prove to be Cullen-regular. The singularities of Cullen-regular functions are thus classified as removable, essential or poles.
Brackx F   +11 more
core   +2 more sources

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Poles of Archimedean zeta functions for analytic mappings

open access: yes, 2011
In this paper, we give a description of the possible poles of the local zeta function attached to a complex or real analytic mapping in terms of a log-principalization of an ideal associated to the mapping.
Leon-Cardenal, E.   +2 more
core   +1 more source

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