Results 41 to 50 of about 14,092,629 (349)
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc +8 more
wiley +1 more source
Perspektif: Jurnal Ilmu-ilmu SosialThis research is motivated by the registration of candidacy through individual channels which are required to use access through the Candidacy Information System (SILON). However, there are still many obstacles in the system starting from the location of
Chandra Gobles Silalahi +2 more
doaj +1 more source
Jaqalanka Limited and Free Trade Zone Workers Union (FTZWU) Dispute Settlement Process: Progress Report from Centre for Policy Alternatives [PDF]
, 2004 This document is part of a digital collection provided by the Martin P. Catherwood Library, ILR School, Cornell University, pertaining to the effects of globalization on the workplace worldwide.
Centre for Policy Alternatives
core +1 more source
Aging and Cancer, EarlyView.Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath +3 more
wiley +1 more source
Turkish Journal of Emergency MedicineThe clinical policy of the Emergency Medicine Association of Türkiye (EMAT) provides guidance on the use of tranexamic acid (TXA) in emergency settings. TXA, an antifibrinolytic drug, is used to control bleeding by inhibiting plasminogen.
Gökhan Aksel +14 more
doaj +1 more source
Theoretical aspects of the implementation of antimonopoly policy in the public management system
Вестник Северо-Кавказского федерального университета, 2023 The author attempts to form a theoretical and methodological approach to assessing the effectiveness of antimonopoly policy. The article postulates that antimonopoly policy has aspects of state regulation and economic content.
D. S. Gukasov
doaj +1 more source
Customized Solutions for Today\u27s Workforce: The Job Accommodation Network [PDF]
, 2005 [Excerpt] The Job Accommodation Network (JAN) is a free and confidential consulting service for employers that expands employment opportunities for individuals with disabilities by providing: ■ Individualized worksite accommodation solutions ■ Technical ...
Office of Disability Employment Policy
core +1 more source
Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source