AI‐Physics‐Experiment Trinity for Integrated Protein Dynamics Modeling
This review unites experiments, physics‐based simulations, and AI as a synergistic triad for protein dynamics modeling. It highlights integrative strategies, resolves sampling and forcefield bottlenecks, and outlines challenges and future directions for accurate, interpretable conformational ensemble prediction.
Chen Shi +4 more
wiley +1 more source
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Because the benefits of broadband for businesses have been widely publicized, the UK government has tried to ensure that there is a wide and fast take-up of
Oni, Oluwasola
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Future Best Buys Can and Should Do More Comment on "Barriers and Opportunities for WHO 'Best Buys' Non-Communicable Disease Policy Adoption and Implementation From a Political Economy Perspective: A Complexity Systematic Review". [PDF]
Abdool Karim S, Faure M.
europepmc +1 more source
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng +14 more
wiley +1 more source
No Time Like the Present: Centring Politics in the Global NCD Policy Agenda Comment on "Barriers and Opportunities for WHO 'Best Buys' Non-Communicable Disease Policy Adoption and Implementation From a Political Economy Perspective: A Complexity Systematic Review". [PDF]
Elliott LM, Topp SM.
europepmc +1 more source
Inhibition of KDELR2 in a small fraction of tumor cells generates sustainable immunogenic cell death conditions within the tumor microenvironment. These conditions promote the regression of tumors in a T cell independent manner. During regression, macrophages prime T cells that subsequently provide systemic protection against recurrence. The potency of
Shakti P Pattanayak +6 more
wiley +1 more source
Finding the Right Balance: Challenges in Optimising the Promise of Complexity Research for NCD Best-Buys Implementation and Adoption Comment on "Barriers and Opportunities for WHO 'Best Buys' Non-communicable Disease Policy Adoption and Implementation From a Political Economy Perspective: A Complexity Systematic Review". [PDF]
Hebbar PB, Bhojani UM, Srinivas PN.
europepmc +1 more source
Advancing smoke-free policy adoption on the Navajo Nation. [PDF]
Nez Henderson P +8 more
europepmc +1 more source
Neuron‐derived MIF binds VCAM1 on gastric cancer cells and activates ERK/STAT3 signaling, leading to CXCL8 transcription and secretion. Tumor‐derived CXCL8 subsequently stimulates neuronal CXCR2 to enhance MIF production, establishing a self‐amplifying MIF–VCAM1–CXCL8 positive‐feedback loop that promotes perineural invasion, tumor progression, and ...
Xunjun Li +13 more
wiley +1 more source
Adoption of Soil Conservation Practices in Olive Groves: The Case of Spanish Mountainous Areas
This paper presents some results from a survey carried out in 2004 among 223 olive tree farmers from mountainous areas in the Spanish Southern provinces of Granada and Jaen regarding the adoption of soil conservation and management practices.
Gonzalez-Roa, Maria del Carmen +2 more
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