Results 31 to 40 of about 5,721,167 (294)

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Policy instrument terms in patriotic health campaign documents issued by Chinese national government agencies from 1952 to 2023: a quantitative textual analysis

Zhongguo gonggong weisheng
ObjectiveTo analyze the historical development and policy structure of China′s Patriotic Health Campaign policy, in order to provide theoretical, methodological and empirical references for the optimization of relevant policies.
Yuanyuan LA, He ZHU, Qiqi WANG, Hongyan YAO, Xiaoyun LIANG   +4 more
doaj   +1 more source

Gridlock and Inefficient Policy Instruments [PDF]

SSRN Electronic Journal, 2016
Why do rational politicians choose inefficient policy instruments? Environmental regulation, for example, often takes the form of technology standards and quotas even when cost‐effective Pigou taxes are available. To shed light on this puzzle, we present a stochastic game with multiple legislative veto players and show that inefficient policy ...
Austen-Smith, David, Dziuda, Wioletta, Harstad, BÃ¥rd, Loeper, Antoine   +3 more
openaire   +4 more sources

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Industrialization process in STPI countries

, 1977
Meeting: Science and Technology Policy Instruments Project, Dissemination Meeting, 14-19 Dec.
Sagasti, F.R., Science and Technology Policy Instruments Project   +1 more
core   +1 more source

A quantitative analysis of development policies for China's assistive technology industry: insights based on the "objective-instrument-intensity" framework

Zhongguo kangfu lilun yu shijian
Objective To quantitatively analyze and evaluate the content of China's assistive technology industry policies. Methods Based on the three-dimensional framework of policy "objectives-instruments-intensity", this study examined 101 national-level ...
Gao Jiamin, Fu Zhenjing, Wang Muxiong, Jiang Xiaqing, Liu Zhihong, Zhang Hongtao   +5 more
doaj   +1 more source

A systematic review of instruments for the analysis of national-level physical activity and sedentary behaviour policies

Health Research Policy and Systems, 2019
Background This systematic review aimed to identify and critically assess available instruments for the analysis of national-level physical activity (PA) and sedentary behaviour (SB) policies and provide recommendations for their future use.
Bojana Klepac Pogrmilovic, Grant O’Sullivan, Karen Milton, Stuart J. H. Biddle, Zeljko Pedisic   +4 more
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

STPI project : approaches and concepts

, 1977
Meeting: Science and Technology Policy Instruments Project, Dissemination Meeting, 14-19 Dec.
Sagasti, F.R., Science and Technology Policy Instruments Project   +1 more
core   +1 more source