Results 41 to 50 of about 825,976 (306)
Translating Policy and Practice [PDF]
Global influences and demographic changes are leading policy makers in less developed countries to look to more developed regions for policy and service ideas. Policy and services ideas may then be `borrowed' via processes such as policy transfer (Dolowitz and Marsh, 1996). This article explores the establishment of day care for people with dementia in
openaire +4 more sources
Lost in Translation: Piloting a Novel Framework to Assess the Challenges in Translating Scientific Uncertainty From Empirical Findings to WHO Policy Statements. [PDF]
BACKGROUND:Calls for evidence-informed public health policy, with implicit promises of greater program effectiveness, have intensified recently. The methods to produce such policies are not self-evident, requiring a conciliation of values and norms ...
Benmarhnia, Tarik +2 more
core +2 more sources
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
The human microbiome is increasingly recognized as a key mediator of health and disease, yet translating microbial associations into actionable interventions remains challenging.
Issam Khelfaoui +10 more
doaj +1 more source
On algorithmic solutions to simple allocation problems [PDF]
We interpret solution rules to a class of simple allocation problems as data on the choices of a policy-maker. We study the properties of rational rules. We show that every rational rule falls into a class of algorithmic rules that we describe. The Equal
Kibris, Ozgur, Kıbrıs, Özgür
core
Long Text Generation via Adversarial Training with Leaked Information [PDF]
Automatically generating coherent and semantically meaningful text has many applications in machine translation, dialogue systems, image captioning, etc.
Cai, Han +5 more
core +2 more sources
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Whilst basic science rapidly produces new insights into the biological determinants of human health and disease, clinical innovation is often said to lag behind, as it fails to rapidly turn such knowledge into new tools for innovative patient care.
Erik Aarden +2 more
doaj +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Building evidence into youth health policy: a case study of the Access 3 knowledge translation forum
Background Effective integration of evidence and youth perspectives into policy is crucial for supporting the future health and well-being of young people. The aim of this project was to translate evidence from the Access 3 project to support development
Daniel Waller +10 more
doaj +1 more source

