Results 61 to 70 of about 829,188 (306)

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

Advanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao, Yejing Zhu, Hengchao Yu, Jun Zhu, Bo Wang, Yu Qiao, Zhimin Tian, Junlong Zhao, Lei Liu   +8 more
wiley   +1 more source

Incorporating translation into sociolinguistic research: translation policy in an international non-governmental organisation [PDF]

, 2017
This article explores aspects of translation, multilingualism and language policy in the field of transnational civil society. By focusing on translation policies at Amnesty International, an international non-governmental organisation that performs a ...
Anderson Mary B., Angelelli Claudia, Bell Allan, Castells Manuel, Codó Eva, Gumperz John J., Hopgood Stephen, Koskinen Kaisa, Lang Sabine, Maryns Katrijn, Rampton Ben, Shetty Salil, Spolsky Bernard, Tesseur Wine, Wolf Michaela   +14 more
core   +2 more sources

Determinants of Vaccine Hesitancy among African American and Black Individuals in the United States of America: A Systematic Literature Review

Vaccines
Despite the crucial role the COVID-19 vaccine played in curbing the pandemic, a significant portion of Black and African American individuals expressed hesitancy toward being vaccinated.
Elena Savoia, Evelyn Masterson, David R. Olander, Emma Anderson, Anisa Mohamed Farah, Luca Pirrotta   +5 more
doaj   +1 more source

Long Text Generation via Adversarial Training with Leaked Information [PDF]

, 2017
Automatically generating coherent and semantically meaningful text has many applications in machine translation, dialogue systems, image captioning, etc.
Cai, Han, Guo, Jiaxian, Lu, Sidi, Wang, Jun, Yu, Yong, Zhang, Weinan   +5 more
core   +2 more sources

Tissue Engineered Human Elastic Cartilage From Primary Auricular Chondrocytes for Ear Reconstruction

Advanced Functional Materials, EarlyView.
Despite over three decades of research, no tissue‐engineered solution for auricular reconstruction in microtia patients has reached clinical translation. The key challenge lies in generating functional elastic cartilage ex vivo. Here, we integrate synergistic cell‐biomaterial strategies to engineer auricular grafts with mechanical and histological ...
Philipp Fisch, Sandra Kessler, Simone Ponta, Anna Puiggalí‐Jou, Guoliang Lyu, Killian Flégeau, Anastasiya Martyts, Florian Roth, David Fercher, Filippo M. Rijli, Daniel Simmen, Eva Novoa Olivares, Thomas Linder, Marcy Zenobi‐Wong   +13 more
wiley   +1 more source

Interventions to Reduce COVID-19 Vaccine Hesitancy among Black and African American Individuals in the United States: A Systematic Literature Review

Vaccines
COVID-19 vaccine hesitancy had major implications for racial health equity at the beginning of the vaccination campaign in the U.S. Interventions to reduce vaccine hesitancy among Black and African American individuals partially helped to reduce vaccine ...
Evelyn Masterson, Emma Anderson, Elena Savoia   +2 more
doaj   +1 more source

Selective reporting bias in randomised controlled trials from two network meta-analyses: comparison of clinical trial registrations and their respective publications

BMJ Open, 2019
Objective To determine (i) the difference in the frequency of serious adverse events (SAEs) reported in trial registrations and their respective primary publications and (ii) the effect of adding SAE data from registries to a network meta-analysis (NMA ...
Sharon E Straus, Andrea C Tricco, Eric KC Wong, Chantelle C Lachance, Jennifer Watt, Areti Veroniki   +5 more
doaj   +1 more source

Translation Policy, Social System, and Ideology: A Study on the English Translation of Modern Chinese Fiction for America During the CWRAJ

SAGE Open, 2021
This article explores translation policy on the English translations of modern Chinese fiction to American readers during China’s War of Resistance against Japan (1931–1945). The research findings show that translation policy may not be explicitly stated,
Ping Li, Chuanmao Tian
doaj   +1 more source

Smart Catheters for Diagnosis, Monitoring, and Therapy

Advanced Healthcare Materials, EarlyView.
This study presents a comprehensive review of smart catheters, an emerging class of medical devices that integrate embedded sensors, robotics, and communication systems, offering increased functionality and complexity to enable real‐time health monitoring, diagnostics, and treatment. Abstract This review explores smart catheters as an emerging class of
Azra Yaprak Tarman, Samiha Ahmed, Majed Othman Althumayri, Megan Guy, Darlenne Chavez Lugo, Frances S. Ligler, George T. Ligler, Rahmi Oklu, Hiroshi Kawahira, Michael J. McShane, Jun Kameoka, Jonathan Bova, Hatice Ceylan Koydemir   +12 more
wiley   +1 more source