Prevalence of five pharmacologically most important CYP2C9 and CYP2C19 allelic variants in the population from the Republic of Srpska in Bosnia and Herzegovina [PDF]
The enzymes of the cytochrome P450 superfamily play a critical role in phase I drug metabolism. Among them, CYP2C9 and CYP2C19 are clinically important, as they can mediate severe toxicity, therapy failure, and increased susceptibility to cancer and ...
Vidović Stojko +6 more
doaj +2 more sources
Metallothionein 2A gene polymorphisms in relation to diseases and trace element levels in humans [PDF]
Human metallothioneins are a superfamily of low molecular weight intracellular proteins, whose synthesis can be induced by essential elements (primarily Zn and Cu), toxic elements and chemical agents, and stress-producing conditions.
Sekovanić Ankica +2 more
doaj +2 more sources
Evaluation of vitamin D, vitamin D binding protein gene polymorphism with oxidantantioxidant profiles in chronic obstructive pulmonary disease [PDF]
Background: The aim was to evaluate the association of plasma 25-hydroxyvitamin D (25-O H D) and vitamin D binding protein (VDBP or Gc-globin) gene polymorphism with oxidant-antioxidant profiles in patients with chronic obstructive pulmonary disease (CO ...
Al-Azzaw Mahmood A. +2 more
doaj +2 more sources
Polimorfizam proteinskih markera semena omorike dobijenog slobodnim oprašivanjem i samooprašivanjem
U cilju utvrđivanja genetičkog polimorfizma i sličnosti odnosno različitosti između genotipova-linija omorike u radu je primenjena analiza u solima rastvorljivih proteina semena, pri čemu smo pošli od predpostavke da oni mogu biti dovoljno informativni ...
Mirjana Šijačić-Nikolić
doaj +6 more sources
Pharmacogenetics of antiretroviral drugs [PDF]
nem
Dragović Gordana +2 more
core +1 more source
U radu su prikazani rezultati proučavanja polimorfizma proteina semena belog (Pinus sylvestris L.) i crnog bora (Pinus nigra Arn.) kao najvažnijih ekonomskih vrsta iz roda Pinus u Srbiji.
Aleksandar Lučić +3 more
doaj +4 more sources
The c.-1639g>A polymorphism of the VKORC1 gene and his influence on the therapeutic response during oral anticoagulants use [PDF]
Background/Aim. A single nucleotide polymorphism c.- 1639G>A in the promoter region of vitamin K-epoxide reductase (VKORC1) gene has been found to account for most of the variability in response to oral anticoagulants (OA). The aim of the study was to
Kovač Mirjana +3 more
core +1 more source
Genetic structure of sessile oak (Quercus petraea (Matt.) Lieblein) in Bosnia and Herzegovina based on the isoenzyme analysis [PDF]
Hrast kitnjak [Quercus petraea (Matt.) Lieblein] jedna je od najvažnijih vrsta šumskog drveća u Bosni i Hercegovini, iako je sadašnja struktura šuma hrasta kitnjaka vrlo slaba.
Dalibor Ballian
core +2 more sources
The importance of tests applied to evaluate the effectiveness of antiplatelet therapy in patients with recurrent coronary stent thrombosis [PDF]
Background. Stent thrombosis is potentially lethal complication with huge economic burden. The role of insufficient response to antiplatelet therapy is still unclear reason for its occurrence. Case report.
Cikota Bojana +10 more
core +1 more source
Variability of albumin in blood serum as a possible reflection of evolutional influence of diluvial horses on population of native mountain horse in Serbia [PDF]
Native mountain horse is an autochthonous ungulata with a domicile extending to the whole mountaneous region of Serbia, south of the Sava and Danube rivers.
Dimitrijević Vladimir +3 more
core +1 more source

