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Self-reported poliomyelitis vaccination and documentation in adults indicates high uptake: a digital German epidemic panel, December 2024. [PDF]
BMC Public HealthKettlitz R +10 more
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Epidemiological indicators of accidental laboratory-origin outbreaks. [PDF]
Epidemiol InfectDhawan S +3 more
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2004
Poliovirus (PV) is the causal agent of paralytic poliomyelitis, an acute disease of the central nervous system (CNS). A killed and an oral live attenuated vaccine were both developed in the 1950s (Salk 1955; Sabin and Boulger 1973), and subsequent massive vaccination campaigns resulted in near total eradication of PV from most industrialized countries:
Blondel, B. +4 more
openaire +3 more sources
Poliovirus (PV) is the causal agent of paralytic poliomyelitis, an acute disease of the central nervous system (CNS). A killed and an oral live attenuated vaccine were both developed in the 1950s (Salk 1955; Sabin and Boulger 1973), and subsequent massive vaccination campaigns resulted in near total eradication of PV from most industrialized countries:
Blondel, B. +4 more
openaire +3 more sources
Annual Review of Genetics, 1993
INFECTIOUS eDNA AND IN VITRO SYNTHESIS OF INFECTIOUS VIRAL RNA 359 SELECTION AND GENERATION OF MUTANTS . . . . . . .... . . .. . . .. . . 360 Selection of Spontaneous Mutants . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 363 Random Mutagenesis .... _ . . . . . . . _ _ .... ... ... _ _ . . . . . . . . . 370 Mutagenesis Targeted to Existing
E, Wimmer, C U, Hellen, X, Cao
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INFECTIOUS eDNA AND IN VITRO SYNTHESIS OF INFECTIOUS VIRAL RNA 359 SELECTION AND GENERATION OF MUTANTS . . . . . . .... . . .. . . .. . . 360 Selection of Spontaneous Mutants . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 363 Random Mutagenesis .... _ . . . . . . . _ _ .... ... ... _ _ . . . . . . . . . 370 Mutagenesis Targeted to Existing
E, Wimmer, C U, Hellen, X, Cao
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Biochemical and Biophysical Research Communications, 1972
Summary Poliovirus, dissociated by exposure to 9 M urea and 0.09 M mercaptoethanol into RNA and protein, can be reconstituted to infectious viral particles by stepwise dilution with cold isotonic phosphate buffered saline at pH 7.2.
R, Drzeniek, P, Bilello
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Summary Poliovirus, dissociated by exposure to 9 M urea and 0.09 M mercaptoethanol into RNA and protein, can be reconstituted to infectious viral particles by stepwise dilution with cold isotonic phosphate buffered saline at pH 7.2.
R, Drzeniek, P, Bilello
openaire +2 more sources
Trends in Biotechnology, 1991
Poliovirus, the aetiological agent of paralytic poliomyelitis, is arguably the best characterized of all animal viruses. Using recombinant-DNA technology, this information, together with the availability of infectious cDNA clones of the notably safe and efficacious live attenuated Sabin 1 vaccine strains of poliovirus, has enabled the creation of ...
C S, Rose, D J, Evans
openaire +2 more sources
Poliovirus, the aetiological agent of paralytic poliomyelitis, is arguably the best characterized of all animal viruses. Using recombinant-DNA technology, this information, together with the availability of infectious cDNA clones of the notably safe and efficacious live attenuated Sabin 1 vaccine strains of poliovirus, has enabled the creation of ...
C S, Rose, D J, Evans
openaire +2 more sources
Clinical Infectious Diseases, 1984
Most of the poliovirus vaccine distributed in the United States since 1962 has been of the live, oral type ( OPV ). Production problems have not been a major concern for the manufacturer. The statistics compiled by various authorities since the product was introduced relative to paralytic disease following the administration of OPV are discussed and ...
openaire +2 more sources
Most of the poliovirus vaccine distributed in the United States since 1962 has been of the live, oral type ( OPV ). Production problems have not been a major concern for the manufacturer. The statistics compiled by various authorities since the product was introduced relative to paralytic disease following the administration of OPV are discussed and ...
openaire +2 more sources