Results 181 to 190 of about 46,021 (228)
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Reconstitution of poliovirus

Biochemical and Biophysical Research Communications, 1972
Summary Poliovirus, dissociated by exposure to 9 M urea and 0.09 M mercaptoethanol into RNA and protein, can be reconstituted to infectious viral particles by stepwise dilution with cold isotonic phosphate buffered saline at pH 7.2.
R, Drzeniek, P, Bilello
openaire   +2 more sources

Stabilisation of poliovirus with pirodavir.

Developments in biological standardization, 1995
Two hundred and forty pyridazinamine derivates were assayed for their ability to stabilize the Oral Polio Vaccine (OPV). Of these, pirodavir (R 77975) was selected for vaccine potency tests. Although pirodavir turned out to be an effective stabilizer of OPV, the protection induced by pirodavir was not better, nor additive to the effect by MgCl2 1 M ...
Rombaut, Bartholomeus   +2 more
openaire   +5 more sources

The Morphogenesis of Poliovirus

1972
Poliovirus is one of the simplest and most extensively studied animal viruses. Yet, in spite of the voluminous literature, many basic and important questions concerning its morphogenesis remain unanswered. For example, what mechanisms insure that the progeny virus retain the precise structural features of the infecting particle ? How does the viral RNA
openaire   +2 more sources

Poliovirus Infection in Guatemala

The American Journal of Tropical Medicine and Hygiene, 1960
Summary The objective of the present study was to determine the frequency of poliovirus infection in Guatemala, primarily the inapparent infections occurring there. Sero-immunity, as indicated by serum neutralization tests in HeLa cell cultures, was demonstrated to all three poliovirus types.
M I, SELLERS   +2 more
openaire   +2 more sources

Translation of Poliovirus mRNA

Enzyme, 2017
Ribosome binding to cellular eukaryotic mRNAs is proposed to occur by initial attachment at or near the mRNA 5' cap structure (m^7 GpppN, where N is any nucleotide) followed by scanning till the appropriate initiator AUG is encountered. A pivotal aspect of this model is the obligatory entry of the ribosomes at the 5' end of the mRNA (regardless if it ...
N, Sonenberg, K, Meerovitch
openaire   +2 more sources

Poliovirus eradication

The Lancet Infectious Diseases, 2012
Masahiko, Hachiya   +3 more
openaire   +4 more sources

Use of inactivated poliovirus vaccine for poliovirus outbreak response

The Lancet Infectious Diseases
With continued wild poliovirus transmission in Afghanistan and Pakistan and circulating vaccine-derived poliovirus in certain countries, there exists an ongoing risk of importation of polioviruses into other countries, including those that have been polio-free for decades.
Ananda S, Bandyopadhyay   +7 more
openaire   +2 more sources

Marker Studies of Poliovirus

Nature, 1966
VARIATION in the chemical properties of the protein coat of different strains has been used as a marker test in investigations of the genetics of polioviruses. Bengtsson, Philipson, Persson and Laurent1 recently showed that a group of these tests had a common basis.
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Poliovirus immunisation for travellers

Travel Medicine and Infectious Disease, 2004
Mass immunisation against poliomyelitis using principally oral live attenuated trivalent vaccine (OPV) has eradicated wild-type poliovirus transmission in the industrialised countries of the Western hemisphere and most other countries, and the global eradication of poliomyelitis is within reach.
openaire   +2 more sources

Poliovirus RNA Replication

1990
The biosynthesis of RNA directed by an RNA template is a reaction that is unique to RNA viruses. Although studies of polio virus RNA synthesis have been conducted in a somewhat intermittent fashion during the past 25 years in several different laboratories, no clear picture has yet emerged regarding the biochemistry of RNA replication for this or any ...
O C, Richards, E, Ehrenfeld
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