Results 131 to 140 of about 799,584 (305)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

The lives of young Polish migrants residing in Northamptonshire [PDF]

open access: yes
This thesis investigates the lives of young Polish migrants living in Northamptonshire, who migrated to the UK following Poland’s accession to the European Union in May 2004. Over 1.1 million Worker Registration Scheme (WRS) applications were made in the
Callender, Matthew
core  

Dos apreciaciones desde el idioma polaco

open access: yesRevista de Lenguas Modernas, 2010
Analizar el idioma ...
Jolanta Wrzodak B.
doaj  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Changes in corporate governance structures in Polish privatised companies [PDF]

open access: yes, 2002
The paper presents early results of the survey of 84 Polish privatised industrial companies, sampled from a list of the 500 biggest firms. Three aspects of corporate governance were analysed: ownership structure, management of the companies, and ...
Kozarzewski, P.
core  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Transformation and its Impact on Structural Changes in Polish Agriculture [PDF]

open access: yes
The following article analyses the structural changes of the Polish agriculture, which have been influenced by the transformation processes. These processes have been caused and influenced by phenomenas of a various scope and impact, but from the point ...
Przygodzka, Renata   +1 more
core  

Expansion of the liverwort Tetralophozia setiformis in the Polish Tatra Mts (Western Carpathians)

open access: yes
The article presents the spread of the liverwort Tetralophozia setiformis in the Polish Tatra Mts (Western Carpathians). In the years 1814-1957 only four localities of this plant have been found in High Tatra Mts.
Górski, Piotr
core   +1 more source

In the realm of simulation war games. Panzer campaigs: Poland ‚39 – the most realistic game about the polish defensive war of 1939 [PDF]

open access: yesAnte Portas
This article discusses the recently released simulation computer game Panzer Campaigns: Poland ‘39 – the most realistic game about the Polish Defensive War of 1939. Characterizing the game’s mechanics, taxonomy, and AI behavior, the author highlights its
Paweł Gotowiecki
doaj  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

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