Results 121 to 130 of about 799,584 (305)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Polish Pavilion

open access: yes, 1939
This poster for the Polish Pavilion at the 1939 World's Fair, held in New York, features four Polish flags with its coat of arms present, flying on poles that stand in front of an image of the 1939 Polish pavilion.
Unknown
core  

Polish YMCA Identification Card for Zofia Krzyżanowska [PDF]

open access: yes, 1943
Polish YMCA identification card no. 49/43 for Zofia Krzyżanowska, Director of the Polish YMCA attached to the Polish Army. Issued January 1, 1943 and valid until January 27, 1944.
Polish YMCA
core  

Pastoral Letter of Polish Bishops on Environmental Protection (May 2, 1989)

open access: yesStudia Ecologiae et Bioethicae, 2020
Polish Bishops' Conference
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Anthroponyms and Toponyms in the Memorial Inscriptions at Cemeteries of National Minorities in Northern Bosnia and Herzegovina

open access: yesВопросы ономастики
The article examines the anthroponyms and toponyms found on gravestone inscriptions at cemeteries in the areas of concentrated settlement of national minorities in northern Bosnia and Herzegovina — namely, Ukrainians, Poles, Czechs, and Italians.
Gleb Petrovich Pilipenko   +1 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

VP-fronting in Czech and Polish : a case study in corpus-oriented grammar research [PDF]

open access: yes, 2005
Fronting of an infinite VP across a finite main verb - akin to German "VP-topicalization" - can be found also in Czech and Polish. The paper discusses evidence from large corpora for this process and some of its properties, both syntactic and information-
Meyer, Roland
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Generics and Context: Do Counterexamples Dissuade Acceptance of True Generic Statements?

open access: yesStudies in Logic, Grammar and Rhetoric
This study investigates whether the salience of counterexamples in discourse affects the acceptance of true generic statements. Building on previous theoretical and experimental work on generics, we examine whether generics are sensitive to contextual ...
Wajda Edyta, Karczewski Daniel
doaj   +1 more source

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