Results 41 to 50 of about 424,329 (269)

Why emerging leaders should focus on being good postdoctoral supervisors

open access: yesFEBS Letters, EarlyView.
Swamped with work and suddenly a new student is waiting at your doorstep for supervision? Great—this is your chance! In this article, we share tips on how postdocs can strengthen their leadership skills while supervising students. This image has been created using DALL·E. Many postdocs work as leaders later in their career.
Hannah Rostalski   +5 more
wiley   +1 more source

Repliki dialogowe informujące o emocjach z pola zdziwienia (na materiale współczesnych utworów prozatorskich napisanych w języku polskim, rosyjskim i angielskim)

open access: yesStudia Linguistica
The aim of the article is to analyze dialogue replicas communicating emotions from the lexical-semantic field of surprise, retrieved from contemporary prose works written in Polish, Russian and English.
Daniel Dzienisiewicz
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Vorschlag als Sprachhandlungsmuster: Methodologie der kontrastiven Analyse am Beispiel des deutsch-polnischen Sprachvergleichs [PDF]

open access: yesBeiträge zur Allgemeinen und Vergleichenden Sprachwissenschaft, 2018
The present paper aims to describe the speech behaviour pattern of PROPOSAL in German and Polish. The term “speech behaviour pattern” refers to the purposeful verbal behaviour.
Elizaveta Kotorova, Tadeusz Zuchewicz
doaj   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Geschlossen, lang oder gespannt? Die Beschreibung der Artikulation niederländischer Vokale aus einer polykonfrontativen (und didaktischen) Perspektive [PDF]

open access: yesLinguistische Treffen in Wrocław
By analyzing the descriptions of Dutch vowels in the selected literature in four languages (Dutch, Polish, German and English), this paper addresses issues at the intersection of terminology and phonetics, while also placing them in the context of ...
Zuzanna Czerwonka-Wajda
doaj   +1 more source

The zinc finger domains of PARP‐1 are selectively and potently inhibited by the Au(I)‐based drugs sodium aurothiomalate and aurothioglucose

open access: yesFEBS Letters, EarlyView.
PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

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