Results 61 to 70 of about 23,979 (269)
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Studia z Filologii Polskiej i Słowiańskiej, 2019 This is a retracted article, whose corrected version, bearing the same title, is avalaible under the DOI: https://doi.org/10.11649/sfps.2235. The correction was introduced at the request of the Author.
Rafał Szeptyński
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Polish Language in the Linguistic Landscape of Vilnius
Acta Baltico-Slavica, 2022 The aim of this article is to analyse the use of Polish-language signs in public space in Vilnius and to identify the reasons for the presence or, conversely, absence of Polish in the linguistic landscape of Vilnius in 2022. The subject of the study is inscriptions in Polish found in public space in the Old Town in Vilnius.
openaire +2 more sources
Uzus a praktyka leksykograficzna (na przykładzie czasownika dedykować we współczesnej polszczyźnie)
Studia z Filologii Polskiej i Słowiańskiej, 2016 Usage and lexicographical practice (example of the verb dedykować ‘to dedicate’ in modern Polish) The purpose of this paper is to analyze the contemporary usage of the Polish verb dedykować (to dedicate) and its participle dedykowany (dedicated).
Monika Biesaga
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Cognitive Studies | Études cognitives, 2018 The coral of your lips, the stars of your eyes – the function of the genitive case in a particular kind of genitive metaphor compared to other semantic functions of this case (based on examples in the Polish language) This paper attempts to explicate ...
Monika Szymańska
doaj +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source