Results 111 to 120 of about 6,321,382 (341)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Czesław Miłosz’ American Experience in Światło dzienne (Daylight)

open access: yesActa Universitatis Lodziensis. Folia Litteraria Polonica, 2016
Miłosz’s volume Światło dzienne (Daylight, 1953) is conventionally read by critics as the political poetry deeply engaged with history. The article offers a corrective to this traditional reading by interpreting the volume as an interplay of European and
Ewa Kołodziejczyk
doaj   +1 more source

Tuwim’s Wedge: 'Survival Strategies' of a Polish-Jewish Poet [PDF]

open access: yes, 2016
Tuwim’s approach to the “Jewish question” has already been analyzed by Polish and foreign scholars. The article is intended to consider some “survival strategies” of the Polish poet from a slightly different angle.
Tomassucci, Giovanna
core   +2 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

The Issa Valley in Censorship Documents. On the Thaw Reception of Czesław Miłosz’s Novel

open access: yesActa Universitatis Lodziensis. Folia Litteraria Polonica, 2016
Czesław Miłosz’s The Issa Valley [Dolina Issy] was published in the Paris Literary Institute in 1955 and soon after started paving its way to readers in the author’s native country, in spite of the censorship.
Marzena Woźniak-Łabieniec
doaj   +1 more source

Promotion of Polish culture in Japan – outline of the situation [PDF]

open access: yes, 2015
W artykule, w pierwszej części, zdefiniowane są główne obszary promocji kultury polskiej w świecie, z podziałem na dwa kierunki: wewnętrzny (terytorium Rzeczypospolitej Polskiej), oraz zewnętrzny (poza granicami Polski).
Rodowicz-Czechowska, Jadwiga
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Miłosz: Self-Reflection as the Topic of a Poetic Description

open access: yesActa Universitatis Lodziensis. Folia Litteraria Polonica, 2016
Czesław Miłosz’s poetry displays two reverberating topics which may be defined as contradictory existence and world experiences. One of those is the admiration for the beauty of the world and awe consequent upon capturing the simultaneous existence of ...
Barbara Stelmaszczyk
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Poetic Lithuania of Miłosz

open access: yesActa Universitatis Lodziensis. Folia Litteraria Polonica, 2016
The article deals with the images of Lithuania found in Czesław Miłosz’s poetry. The novels and essays have only been used to confirm the conclusions drawn from the interpretation of selected poems.
Maria Berkan-Jabłońska
doaj   +1 more source

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