Results 101 to 110 of about 85,251 (307)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Poetic Lithuania of Miłosz

open access: yesActa Universitatis Lodziensis. Folia Litteraria Polonica, 2016
The article deals with the images of Lithuania found in Czesław Miłosz’s poetry. The novels and essays have only been used to confirm the conclusions drawn from the interpretation of selected poems.
Maria Berkan-Jabłońska
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Playing Chopin backwards. Kuncewicz's and Themerson's transnational Polish literature

open access: yes
My doctoral thesis investigates the construction of a transnational paradigm for Polish literature in the activities and works of Maria Kuncewicz and Stefan Themerson.
Sidorkiewicz, Ola
core   +1 more source

The past and the present: a historical outline of Polish research into translations of children’s and young adult literature. Introduction

open access: yes, 2020
The purpose of this contibution is to examine the historical outline of Polish research into translations of children’s and young adult literature, especially between the XXth and the XXIst century.
Biernacka-Licznar, K   +2 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Polish literature in lithuanian and the lithuanian literature in polish languages (1991-2006)

open access: yes, 2008
Straipsnyje pateikiami nauji lyginamųjų literatūrologinių tyrimų duomenys apie lenkų literatūrą lietuvių kalba ir lietuvių literatūrą lenkų kalba, išleistą per paskutinius penkiolika metų.
Dalecka, Teresa
core  

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