Results 81 to 90 of about 415,740 (306)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

NeoWestern business-government relations: the case of Poland [PDF]

open access: yes, 2005
This article investigates the applicability of Western models of business-government relations to the postcommunist context. Given the absence of a business-government relationship over the forty years of communism, it seems perfectly plausible that ...
McMenamin, Iain
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Conrad: The Critical Response, 1950-75 [PDF]

open access: yes, 2009
Following his positioning as a major English novelist by F.R. Leavis in The Great Tradition (1948), Conrad became a central figure in academic literary criticism in the 1950s and 1960s with the publication of a series of seminal works on the writer. With
Niland, Richard
core   +3 more sources

Promotion of Polish culture in Japan – outline of the situation [PDF]

open access: yes, 2015
W artykule, w pierwszej części, zdefiniowane są główne obszary promocji kultury polskiej w świecie, z podziałem na dwa kierunki: wewnętrzny (terytorium Rzeczypospolitej Polskiej), oraz zewnętrzny (poza granicami Polski).
Rodowicz-Czechowska, Jadwiga
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

“I owed a great deal to them”. Some hypotheses about the paradoxes of Jewish assimilation in Gombrowicz’s works

open access: yesPl.it, 2020
My aim is to contextualise and reflect on the ambivalences of Gombrowicz’s view of the interwar Polish Jews both in his satirical short story The Brief Memoir of Jakób Czarniecki (1933), focused on the mechanisms of the exclusion of Jews from the Polish ...
Giovanna Tomassucci
doaj  

THE EVOLUTION OF THE DETECTIVE GENRE IN CULTURAL CONTEXTS: COMPARATIVE ANALYSIS OF KAZAKH, POLISH AND WESTERN LITERATURE [PDF]

open access: yesЕзиков свят
The detective fiction, as one of the most engaging genres of literature, occupies a significant place in the literary traditions of various cultures. Since its emergence in the 19th century, the genre has evolved under the influence of diverse social ...
Elnara Mansurova   +2 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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