FeS‐VA@lanifibranor (FVL), an activated hepatic stellate cell (aHSC)‐targeted nanoplatform comprising vitamin A‐functionalized two‐dimensional iron sulfide nanosheets and lanifibranor, is engineered for precision therapy of liver fibrosis. FVL suppresses the TGF‐β signaling pathway by inhibiting SMAD2/3 phosphorylation and induces ferroptosis in aHSCs,
Yinuo Yang +11 more
wiley +1 more source
Impact of an Influenza and Pneumococcal Vaccination Course on Enhancing Pharmacists' Knowledge. [PDF]
Waszkiewicz M +4 more
europepmc +1 more source
Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu +4 more
wiley +1 more source
Beverage Consumption Patterns, Beverage-Derived Energy Intake, and Adherence to Fluid Intake Recommendations Among Polish Adolescents: A Cross-Sectional Study Using the BEVQ-PL Questionnaire. [PDF]
Zborowski M, Skotnicka M.
europepmc +1 more source
Conventional therapies suffer from poor blood–brain barrier (BBB) penetration and disordered ion/reactive oxygen species (ROS) homeostasis, hindering precise neurological treatment. Electrochemical strategies achieve accurate spatiotemporal regulation of neural homeostasis.
Xiaokang Hu +5 more
wiley +1 more source
Interhospital Transportation of Pediatric Patients Undergoing Venovenous Extracorporeal Membrane Oxygenation (VV ECMO) Support-A 3-Year Regional Experience. [PDF]
Kociński B +8 more
europepmc +1 more source
Application of a zwitterionic poly(sulfobetaine methacrylate) (PSB) coating to microelectrode arrays and Ag/AgCl reference electrodes effectively inhibits biofouling and structural degradation. This strategy successfully enables simultaneous, long‐term electrophysiological recording and dopamine sensing in freely behaving mice, facilitating ...
Bingchen Wu +5 more
wiley +1 more source
Chemical Strategies for Multistimuli Responsive Dynamic Covalent Materials in Regenerative Medicine
Multistimuli responsive dynamic covalent materials integrate reversible chemistry with the complex chemical, mechanical, and biochemical cues of regenerative environments. This review highlights chemical strategies based on orthogonal dynamic bonds, multicomponent networks, and hierarchical architectures to regulate mechanics, degradation, and ...
Saurabh Joshi +2 more
wiley +1 more source
Evaluation of augmented reality for interstitial brachytherapy optimisation: a prospective phantom-based study protocol and preliminary results. [PDF]
Chyrek AJ, Kluska A, Bielęda G.
europepmc +1 more source

