Results 21 to 30 of about 6,862 (217)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Journal of Functional Analysis, 1988 If Y is a Banach space and a separable Banach space \(X\subset Y\) *, then X is said to be w *-Polish if the closed unit ball of X is Polish in the w *-topology (i.e. homeomorphic to a separable complete metric space). This property of Banach spaces is carefully studied in connection to properties like the point of continuity property, skipped blocking
openaire +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Descriptive Complexity on Non-Polish Spaces.
, 2020 Represented spaces are the spaces on which computations can be performed. We investigate the descriptive complexity of sets in represented spaces. We prove that the standard representation of a countably-based space preserves the effective descriptive complexity of sets.
Callard, Antonin, Hoyrup, Mathieu
openaire +3 more sources
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
REPRESENTATIONS OF IDEALS IN POLISH GROUPS AND IN BANACH SPACES [PDF]
The Journal of Symbolic Logic, 2015 AbstractWe investigate ideals of the form {A⊆ω: Σn∈Axnis unconditionally convergent} where (xn)n∈ωis a sequence in a Polish group or in a Banach space. If an ideal onωcan be seen in this form for some sequence inX, then we say that it is representable inX.After numerous examples we show the following theorems: (1) An ideal is representable in a Polish ...
Piotr Borodulin-Nadzieja +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
A Q-WADGE HIERARCHY IN QUASI-POLISH SPACES [PDF]
The Journal of Symbolic Logic, 2020 AbstractThe Wadge hierarchy was originally defined and studied only in the Baire space (and some other zero-dimensional spaces). Here we extend the Wadge hierarchy of Borel sets to arbitrary topological spaces by providing a set-theoretic definition of all its levels.
openaire +3 more sources
Nonreduction of Relations in the Gromov Space to Polish Actions [PDF]
Notre Dame Journal of Formal Logic, 2018 It is shown that, in the Gromov space of isometry classes of pointed proper metric spaces, the equivalence relations defined by existence of coarse quasi-isometries or being at finite Gromov-Hausdorff distance, cannot be reduced to the equivalence relation defined by any Polish action.
Álvarez López, Jesús A. +1 more
openaire +6 more sources