Results 71 to 80 of about 7,125 (266)

Random Common Fixed Point Theorems for Two Pairs of Nonlinear Contractive Maps in Polish Spaces

International Journal of Analysis and Applications, 2020
This research work proves the random common fixed point theorem for two pairs of random weakly compatible mappings fulfilling certain generalized random nonlinear contractive conditions in Polish spaces. An example is given to support the validity of our
Kanayo Stella Eke, Hudson Akewe, Jiemvwo Godwin Oghonyon   +2 more
doaj  

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Demand for and Development of Greenery in Historic Town Squares: The Case of Zakliczyn

Technical Transactions
This article explores the historic development of greenery in market square spaces using the example of the Polish town of Zakliczyn in Lesser Poland. Contemporary Polish conservation policy aimed at preserving a public space’s historic values is often ...
Kania Olga Dagmara, Hess Daniel Baldwin
doaj   +1 more source

Chains of Dense G_δ Sets in Perfect Polish Spaces

International Journal of Topology
We prove that in every nonempty perfect Polish space, every dense Gδ subset contains strictly decreasing and strictly increasing chains of dense Gδ subsets of length c, the cardinality of the continuum. As a corollary, this holds in Rn for each n≥1. This
Sidney A. Morris
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Barriers and accessibility in public squares: evidence from small towns in Upper Silesia (Poland)

Bulletin of Geography. Socio-Economic Series
Citizens have a fundamental right to access public spaces. Since the adoption of the UN Convention on the Rights of Persons with Disabilities in 2008, significant changes have been made to Polish law.
Justyna Kleszcz, Anna Szczegielniak, Marcin Gałkowski, Weronika Brożyna, Monika Ewa Adamska, Arkadiusz Mordak, Ewa Kulińska, Dariusz Masłowski   +7 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Random Periodic Point and Fixed Point Results for Random Monotone Mappings in Ordered Polish Spaces

Fixed Point Theory and Applications, 2010
The measurability of order continuous random mappings in ordered Polish spaces is studied. Using order continuity, some random fixed point theorems and random periodic point theorems for increasing, decreasing, and mixed monotone random mappings are ...
Zhu Xing-Hua, Xiao Jian-Zhong
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source