Results 51 to 60 of about 6,751,333 (339)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Special Issue Introduction

open access: yesIdentities
This Special Issue of Identities: Journal for Politics, Gender and Culture is result of implementation of a project „Public Capacity for a Just Green Transition“ funded by the Bulgarian National Science Fund under contract KП-06 Н55/13 (period November ...
Identities Journal for Politics, Gender and Culture
doaj   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Menorah Review (No. 80, Winter.Spring, 2014) [PDF]

open access: yes, 2014
Author\u27s Reflections on Politics in the Bible -- Books in Brief: New and Notable -- Masada -- Nazism and Politics -- night trains -- Salvation Through Transgression -- Shoah: The First Day -- The Jewish World of Herbert ...

core   +1 more source

Downregulation of sST2, a decoy receptor for interleukin‐33, enhances subcutaneous tumor growth in murine pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto   +5 more
wiley   +1 more source

Mediating urban politics [PDF]

open access: yes, 2009
Despite the turn to relational vocabularies in urban theory, most work on urban politics acknowledging the importance of media has tended to reproduce a centred image of ‘the media’ and a functionalist account of mediation.
Amin   +21 more
core   +3 more sources

The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells

open access: yesFEBS Open Bio, EarlyView.
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel   +8 more
wiley   +1 more source

A faded passion? Estes Kefauver and the senate subcommittee on antitrust and monopoly [PDF]

open access: yes, 2007
In this paper I examine the U.S. Senate subcommittee on antitrust and monopoly (1957-1963), chaired by Tennessee Senator Estes Kefauver. I assess the persistence into the postwar years of the antimonopoly critique of bigness that had animated the ...
Scroop, D.
core  

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Book review: history, heritage and tradition in contemporary British politics [PDF]

open access: yes, 2012
This book explores the use of the past in modern British politics. It examines party political perspectives on British history and the historical process, and also looks at the ways in which memory is instituted within the parties in practice, through ...
Cowman, Krista
core  

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