Results 31 to 40 of about 130,543 (268)
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
This paper aims to analysis the dynamics related to the policy making process related to its structure and forms of argument analysis. Based on the research was conducted in Makassar, within the framework of policy system, this research describes the ...
Muhammad Saad, Sukri Tamma
doaj +1 more source
Post-election survey data: Local democracy and the 2018 local elections in the Czech Republic
This article presents unique survey data focused on local democracy, political attitudes and political participation. The main aim of the research was to understand the relationships between political values, political participation, political knowledge ...
Pavel Šaradín +5 more
doaj +1 more source
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Introducing the Archive of Interwar Europe Election Data & Assemblies (AIEEDA)
We describe the Archive of Interwar Europe Election Data and Assemblies (AIEEDA), a new multi-level dataset of parliamentary elections in interwar Europe (1919-1939).
Lea Kaftan +5 more
doaj +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Nigeria has been entrapped in a cycle of insecurity which has not only affected the lives and properties of its citizens, but as had a colossal effect on the macro-economy of the state.
Ibrahim O. SALAWU +3 more
doaj +1 more source
Aristotle’s Politics: Ethical Politics or Political Realism?
Much of the scholarly literature provides significant support for the ethical foundation of Aristotelian political science. Still, it cannot be said that there is a smooth relationship between Aristotle’s ethical thinking and his theory of politics in the Politics.
openaire +3 more sources
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source

