Results 51 to 60 of about 134,392 (268)

Too much or never enough: mattering and adolescent ill-being. revisiting social pathologies through the schism between hyper-significance and invisibility

International Journal of Adolescence and Youth
Adolescent illbeing is often framed as individualized mental health problems through medicalized language. Drawing on Durkheim’s concepts of regulation and disintegration and Prilleltensky’s theory of mattering, this article reconceptualizes adolescent ...
Iben Lausten Kragh, Betina Skov Jacobsen, Anna Ryberg Kjær   +2 more
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

The impact of servant leadership on employees taking charge behavior

Scientific Reports
This study investigates the impact of servant leadership on employees’ taking charge behavior, focusing on the mediating roles of intrinsic motivation and supervisor-subordinate relationships, and the moderating effect of employees’ hierarchical levels ...
Miao Hu, Yicheng Wang, Xinrui Xu, Zhouzhou Lin, Yishuai Yin   +4 more
doaj   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source

LLM-generated messages can persuade humans on policy issues

Nature Communications
The emergence of large language models (LLMs) has made it possible for generative artificial intelligence (AI) to tackle many higher-order cognitive tasks, with critical implications for industry, government, and labor markets.
Hui Bai, Jan G. Voelkel, Shane Muldowney, Johannes C. Eichstaedt, Robb Willer   +4 more
doaj   +1 more source

Evaluation of Availability of Human, Scientific, Technological and Innovative Potential in the Context of Priorities in Scientific and Technological Development of the Russian Federation

Интеграция образования, 2018
Introduction. The implementation of priorities of the scientific and technological development of the Russian Federation involves an assessment of the trends in the development of human, scientific, technological and innovation potential within the ...
Magomed Sh. Mintsaev, Irina E. Ilina, Svetlana L. Parfenova, Vladislava N. Dolgova, Elena N. Zharova, Elizaveta V. Agamirova   +5 more
doaj   +1 more source

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou, Marc Jaskir, Julian Gal, Yombe Fonkeu, Christos Davatzikos, MacLean P. Nasrallah, Jose Garcia, Rubo Xing, Stephen J. Bagley, Arati Desai, Richard E. Phillips, Steven Tobochnik, Colin A. Ellis, James J. Gugger, Nishant Sinha, Joel M. Stein, Kathryn A. Davis   +16 more
wiley   +1 more source

From Regional Forums to NATO Alignment: Institutional Adaptation in the Context of Sweden and Finland’s Accession [PDF]

Međunarodna politika
Russia’s invasion of Ukraine in early 2022 reshaped the foundations of European security. In response, Sweden and Finland abandoned decades of military nonalignment and transitioned towards NATO membership.
Ana Jović-Lazić, Stefan Bošković
doaj   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

Regional energy projects in the Eurasian area [PDF]

Industrija, 2012
The Eurasian area has a very rich energy reserves, and is characterized by a complex network of relationships between major suppliers and consumers. The central place in this area has Russia as a country richest in energy resources in Eurasia. Beside her,
Antevski Miroslav, Petrović Pero, Vesić Dobrica   +2 more
doaj